AMR Advanced Medical Research

01/09/2019

Is a zero rate of blood transfusion in patients undergoing THA who have a preoperative Hb less than 12 attainable?

Purpose Pre-operative anaemia treatment has been associated with reduced morbidity in joint arthroplasty. This study examined the impact of a surgical prescription of epoetin (EPO) in contemporary...

28/03/2017

Constraint choice in revision knee arthroplasty: study protocol of a randomised controlled trial assessing the effect of level of constraint on postoperative outcome.http://bmjopen.bmj.com/content/bmjopen/7/3/e012964.full.pdf

15/03/2017

Background: Patient-specific instrumentation (PSI) was introduced with the aim of making the procedure of total knee arthroplasty more accurate and efficient. The purpose of this study was to compare PSI and standard instrumentation in total knee arthroplasty with regard to radiographic and clini...

23/03/2016

Surgical patients experience inadvertent hypothermia as a result of anaesthesia-induced thermoregulatory impairment. Previous studies have found that hypothermia is associated with increased blood loss and transfusion requirements. This study examined the incidence of hypothermia in patients undergo…

08/03/2015

Single dose intravenous tranexamic acid as effective as continuous infusion in primary total knee arthroplasty.

http://1.usa.gov/1GuQ2gV

Arch Orthop Trauma Surg. 2015 Feb 10. [Epub ahead of print]

11/11/2014

Another project published! AMR contributed to the book "Developments in Statistical Evaluation of Clinical Trials" with a section on competing risk.

http://bit.ly/1zgNblg

This book describes various ways of approaching and interpreting the data produced by clinical trial studies, with a special emphasis on the essential role that biostatistics plays in clinical trials.Over the past few decades the ...

20/10/2014

A health-economic study conducted in collaboration with AMR has shown that unicondylar knee replacement yields clear advantages in terms of costs and marginal advantages in terms of health effects, in comparison with total knee replacement.

http://bit.ly/1vAzxte

To view the full text, please login as a subscribed user or purchase a subscription. Click here to view the full text on ScienceDirect.

01/08/2014

Patient-specific instrumentation (PSI) was introduced with the aim of improving alignment after total knee arthroplasty (TKA). A meta-analysis concluded that PSI does not improve the accuracy of alignment of the components in TKA compared with conventional instrumentation.

http://bit.ly/WR6HYf

We conducted a meta-analysis, including randomised controlled trials (RCTs) and cohort studies, to examine the effect of patient-specific instruments (PSI) on radiological outcomes after total knee replacement (TKR) including: mechanical axis alignment and malalignment of the femoral and tibial comp…

26/07/2014

Advanced bearings can be considered a cost-effective solution in total knee arthroplasty compared to standard articulations, particularly in younger patients.


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AMR Advanced Medical Research is a contract research organization that specialises in medical writing and clinical research.

03/07/2014

A meta-analysis showed that there are no essential differences between fixed and mobile bearing UKA designs.


http://bit.ly/1qpsLDL

Two design concepts are currently used for unicondylar knee arthroplasty (UKA) prostheses: fixed bearing (FB) and mobile bearing (MB). While MB prostheses have theoretical advantages over their FB counterparts, it is not clear whether they are associated with better outcomes. A systematic review was…

21/12/2013

...and the research goes on and on.. "Delaying The First Rivaroxaban Dose Has A Modest Impact On Bleeding After Total Hip Replacement", authors H. Hourlier and P. Fennema, has been accepted for Free Paper oral presentation at the 15th EFORT Congress, 4 - 6 June 2014.

30/11/2013