SunyBiotech

24/06/2024

Dominic F. Bennett’s research team from University of Liverpool published an article entitled "Rilmenidine extends lifespan and healthspan in Caenorhabditis elegans via a nischarin I1-imidazoline receptor" in Aging Cell.

In this article, there are 3 strain generated by our company (SunyBiotech).

Our generated strains 🪱🪱:
"PHX893
PHX116
PHX117"

More details please check👇

Aging Cell is an open access geroscience journal addressing the biology of aging, from molecular mechanisms of aging to age-related disease.

11/06/2024

Christopher C Quinn’s research team from University of Wisconsin-Milwaukee published an article entitled "Autism candidate gene rbm-26 (RBM26/27) regulates MALSU-1 to protect against mitochondrial dysfunction during axon development" in bioRxiv.

In this article, there are 2 strain generated by our company (SunyBiotech).

Our generated strains 🪱🪱:
"malsu-1(syb6330)
rbm-26(syb2552 [rbm-26::scarlet::AID])"

More details please check👇

Mitochondrial dysfunction is thought to be a key component of neurodevelopmental disorders such as autism, intellectual disability, and ADHD. However, little is known about the molecular mechanisms that protect against mitochondrial dysfunction during neurodevelopment. Here, we address this question...

30/05/2024

We are delighted to have contributed to the BAWM-Bay Area Worm Conference. Congratulations on a successful conference!🥳

Here are some photos from the scene. Our cute nematode plush toy and logo were shown in the photos, and our customer hung our toy in her office.🥰

For more information please check👇
https://sites.google.com/csueastbay.edu/bawm-2024/home-base

21/05/2024

Margot Thome-Miazza’s research team from University of Lausanne published an article entitled "MALT-1 shortens lifespan by inhibiting autophagy in the intestine of C. elegans" in Autophagy Reports.

In this article, there are 4 strain generated by our company (SunyBiotech).

Our generated strains 🪱🪱:
syb492
syb6548
syb6791
syb629

More details please check👇

The caspase-like protease MALT1 promotes immune responses and oncogenesis in mammals by activating the transcription factor NF-κB. MALT1 is remarkably conserved from mammals to simple metazoans dev...

15/05/2024

Keiko Gengyo-Ando’s research team from Tohoku University published an article entitled "Domain 3a mutation of VPS33A suppresses larval arrest phenotype in the loss of VPS45 in Caenorhabditis elegans" in microPublication Biology.

In this article, there are 1 strain generated by our company (SunyBiotech).

Our generated strains 🪱🪱:
syb8647

More details please check👇

2Bioinformatics Unit, Research Center for Advanced Analysis, National Agriculture and Food Research Organization, Tsukuba, Ibaraki, Japan

10/05/2024

Eric Gouaux’s research team from Oregon Health and Science University published an article entitled "The structure of the Caenorhabditis elegans TMC-2 complex suggests roles of lipid-mediated subunit contacts in mechanosensory transduction" in PNAS.

In this article, there are 2 strains generated by our company (SunyBiotech).

Our generated strains 🪱🪱:
syb2106
syb4776

More details please check👇

08/05/2024

Guy M. Benian’s research team from Emory University published an article entitled "The RhoGAP RRC-1 is required for the assembly or stability of integrin adhesion complexes and is a member of the PIX pathway in muscle" in Molecular Biology of the Cell.

In this article, there are 4 strains generated by our company (SunyBiotech).

Our generated strains 🪱🪱:
PHX647
PHX632
PHX4499
PHX5908

More details please check👇

GTPases cycle between active GTP bound and inactive GDP bound forms. Exchange of GDP for GTP is catalyzed by guanine nucleotide exchange factors (GEFs). GTPase activating proteins (GAPs) accelerate GTP hydrolysis, to promote the GDP bound form. We reported that the RacGEF, PIX-1, is required for ass...

29/04/2024

Olli Matilainen’s research team from University of Helsinki
published an article entitled "Folate receptor overexpression induces toxicity in a diet-dependent manner in C. elegans" in Scientific Reports.

In this article, there are 4 strains generated by our company (SunyBiotech).

Our generated strains 🪱🪱:
PHX4116
PHX5135
PHX4185
PHX7330

More details please check👇

Folate receptor (FR) alpha (FOLR1) and beta (FOLR2) are membrane-anchored folate transporters that are expressed at low levels in normal tissues, while their expression is strongly increased in several cancers. Intriguingly, although the function of these receptors in, for example, development and c...

26/04/2024

Bingsen Zhang, Frank C. Schroeder’s research team from Cornell University published an article entitled "Amino acid and protein specificity of protein fatty acylation in C. elegans" in PNAS.

In this article, there are 3 strains generated by our company (SunyBiotech).

Our generated strains 🪱🪱:

PHX8149(syb8149)
PHX8254(syb8254)
3xflag-dhhc-10 overexpression strain

More details please check👇

Protein lipidation plays critical roles in regulating protein function and localization. However, the chemical diversity and specificity of fatty a...

25/04/2024

Shai Shaham’s research team from The Rockefeller University
published an article entitled "LET-381/FoxF and its target UNC-30/Pitx2 specify and maintain the molecular identity of C. elegans mesodermal glia that regulate motor behavior" in the EMBO Journal.

In this article, there are 6 strains generated by our company (SunyBiotech).

Our generated strains 🪱🪱:
PHX3025
PHX2879
PHX4689
PHX5792
PHX5704
PHX5759

More details please check👇

18/04/2024

Paschalis Kratsios’s research team from University of Chicago
published an article entitled "A molecular atlas of adult C. elegans motor neurons reveals ancient diversity delineated by conserved transcription factor codes" in Cell Reports.

In this article, there are 6 strains generated by our company (SunyBiotech).

Our generated strains 🪱🪱:

syb2307
syb6730
syb2361
syb2679
syb4759
syb3411

More details please check👇:

Smith et al. provide a gene expression map of adult C. elegans motor neurons, uncovering striking diversity and conserved molecular codes of transcription factor genes.

10/04/2024

Meng Wang’s research team from HHMI Janelia Research Campus
published an article entitled "Organelle proteomic profiling reveals lysosomal heterogeneity in association with longevity" in eLife.

In this article, there are 6 strains generated by our company (SunyBiotech).

Our generated strains 🪱🪱:
syb7950
syb4893
syb4827
syb5019
syb4805
syb8005

More details please check👇:

First systemic lysosomal proteomes in association with longevity and tissue specificity in C. elegans uncover lysosomal heterogeneity across multiple scales and provide valuable resources for understanding how lysosomes modulate signal transduction, organelle communication, tissue physiology, and or...