29/09/2025
Stimulate the brain to relieve pain:
The benefits of active sitting are likely to go far beyond the activation and strengthening of core muscles. And it is likely that the reduction in chronic low back, neck and shoulder pain often experienced by office workers when they exchange their conventional office chair for a SpinaliS active sitting chair cannot simply be attributed to having greater core muscle activation and/or strength.
Chronic or long-term pain involves brain changes, not simply muscle weakness. The brain areas that process pain become more sensitive, and in many people with long-term pain have been shown to activate spontaneously; without any or with only minimal stimulation of pain nerves signalling injury or excessive biomechanical loading of muscles, tendons, joints or ligaments (1). In addition to this, brain areas that are meant to dampen pain perception and processing work less efficiently; this is known as poor endogenous pain modulation. Unfortunately, a major risk factor for developing such brain changes that can lead to chronic pain is having a sedentary lifestyle (2,3,4) Several recent studies (5,6,7,8) have shown exercise programmes involving core muscle strengthening, motor control and/or balance training to be effective in reducing chronic low back pain. Such exercises will not only strengthen muscles, but they will also activate brain areas associated with balance and coordination of movement (cerebellum, vestibular system, frontal lobe motor areas). This, in turn, can directly or indirectly stimulate brain areas involved in endogenous pain modulation, e.g. raphe nuclei, nucleus tractus solitarius, periaqueductal gray and hypothalamus (9,10,11,12,13).
Training the spinal muscles through active sitting will also improve what is known as pain-gating. A well-known example of pain-gating is when you accidently knock your elbow and instinctively rub it to make it hurt less. The basic principle is to activate nerve fibres that transmit a non-painful signal (rubbing) as this partially blocks the transmission and processing of pain nerve signals. Nerve signals from muscles, that signal muscle length and speed of stretch (proprioception), also powerfully activate the pain gates, and therefore help to reduce the transmission and processing of pain (14). Muscles that have better muscle tone and are activated regularly produce better pain-gating. So training the spinal muscles through active sitting is likely to produce better pain-gating for people with back pain.
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Fuller et al. describe a novel role of proprioceptive parvalbumin-expressing sensory neurons in the tonic inhibition of nociceptive signalling within dorsa