05/14/2026
🧠 Comment or DM concussion for a concussion protocol.
The concussion isn’t what destroys the brain. What happens in the 6 months after is.
Mechanical impact stretches neuronal membranes, potassium effluxes out, calcium influxes in, the mitochondria get overwhelmed with calcium, and that’s what triggers the reactive oxygen species cascade and the energy crisis.
4 compounds in the literature target it:
OMEGA-3 (DHA + EPA)
The brain is built from DHA.
DHA is roughly 10-20% of total brain fatty acids,
DHA rebuilds damaged membranes.
EPA + DHA also convert into resolvins and protectins, what the literature calls Specialised Pro-Resolving Mediators (SPMs).
SPMs aren’t anti-inflammatory. They’re pro-resolution. They actively shut inflammation down rather than block it.
Athletes supplementing omega-3 across a season showed attenuated rises in neurofilament light chain, a biomarker of axonal injury (Oliver, 2021).
Dose: 4-6g total omega-3/day, DHA-emphasised, triglyceride form.
CREATINE
Brain runs on ATP. After concussion, an energy crisis occurs.
Creatine restores phosphocreatine stores in neurons.
For cognition under stress: 10g/day.
For sleep deprivation: up to 20g.
For concussion or active brain injury: 30g+/day.
CURCUMIN (Meriva)
NF-κB inhibition and COX-2 down-regulation.
It blocks the inflammatory pathway driving secondary injury.
Standard curcumin barely absorbs. Meriva (lecithin phytosome) gets 29x better absorption.
Dose: 1000mg day.
THE TIER STRUCTURE
Tier 1 (foundation): Zinc, Magnesium, Omega-3, Creatine. Start day one.
Tier 2 (oxidative defence): NAC, Melatonin, Glutathione. Add within 72 hours if possible.
Tier 3 (targeted): Curcumin, Boswellia, DHEA, Pregnenolone. Add if symptoms persist past 2-4 weeks.
You can’t rest your way out of a concussion. Metabolic injury requires metabolic support.
🧠 Comment or DM concussion for the full concussion protocol.