02/06/2023
Leaky gut is only one of the detrimental aspects of artificial sweeteners.
"Other studies have found that sucralose can adversely affect gut health, so we wanted to see what might be happening there," Schiffman says. "When we exposed sucralose and sucralose-6-acetate to gut epithelial tissues – the tissue that lines your gut wall – we found that both chemicals cause 'leaky gut.' Basically, they make the wall of the gut more permeable. The chemicals damage the 'tight junctions,' or interfaces, where cells in the gut wall connect to each other.
A new study finds a chemical formed when we digest a widely used sweetener is "genotoxic," meaning it breaks up DNA.
