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Asceleración Empresa dedicada a la innovación, transformación y ascenso de empresas a través de aprendizaje con experimentación.

07/09/2026

You should be failing about 15% of the time. On purpose.

That's the finding from machine-learning researchers at the University of Arizona and Princeton: systems learn fastest when they succeed about 85% of the time. Not 100. Not 50. Eighty-five.

The logic holds for people. Succeed constantly and the task is too easy to teach you anything. Fail constantly and it's all noise, no signal. Growth lives in the band between — stretched, but not snapped.

Which means a perfect track record isn't proof you're excellent. It's often proof you're under-challenged.

Pick one goal you're working on right now. Dial the difficulty until you're succeeding eight or nine times out of ten. Winning daily? Raise the bar. Losing most days? Lower it, without shame — that's calibration, not surrender.

And expect it to feel uncomfortable. That discomfort isn't failure. It's the emotional signature of learning.

What's one goal you'd have to stretch — or shrink — to hit 85%?

27/08/2026

A personalized mRNA cancer vaccine has become the first of its kind to clear a Phase 3 clinical trial, putting it on a potential path toward FDA approval.

Unlike traditional cancer treatments that use a one-size-fits-all approach, researchers tailor each vaccine to target a patient’s cancer cells, giving the immune system the genetic instructions it needs to identify and attack the tumor. The trial included more than 1,000 melanoma patients at risk of recurrence, offering researchers insights into how this treatment could fit into cancer care. https://on.natgeo.com/ZH55Tc

27/08/2026

Grape growers in Mexico have a new tool to fight powdery mildew, a common fungal disease, after the country became the first in the world to approve the commercial sale of an RNA-based biofungicide.

Oifirax, developed by the U.S. company GreenLight Biosciences, uses RNA molecules to silence a gene essential for the survival of the disease-causing fungus Erysiphe necator.

The Mexican government announced the product's commercial approval earlier this August, following a 9-month regulatory process involving the country's health, agricultural, and environmental authorities.

Learn more: https://scim.ag/4ixe6aT

17/08/2026

The startup Ferveret, founded by former MIT nuclear engineering postdoc Reza Azizian and MIT nuclear science and engineering Professor Matteo Bucci, is adapting an approach from nuclear reactors to cool the chips that run AI models using no water and significantly less electricity.

The company’s cooling system submerges computer servers in a specialized liquid that absorbs heat much more efficiently than air from a fan. What makes the solution different from other liquid cooling systems is that it produces much smaller bubbles at the surface of the server, which detach more frequently, accelerating the heat transfer process.

“Our goal is to make data centers as sustainable as possible and help them use every single watt of power to generate tokens, which are the most useful outputs,” Azizian says. “Our system enables the operation of more powerful chips, it helps data centers waste a lot less energy, and it accomplishes all that with zero water consumption.”

📸: Courtesy of Ferveret

https://news.mit.edu/2026/nuclear-inspired-cooling-system-ferveret-could-make-data-centers-more-sustainable-0610

15/08/2026

On National Financial Awareness Day, read Fixed and learn from two leading economists who explain why today’s personal finance markets are rigged against us and offer practical steps to fix them!

With the explosive growth of the global middle class, longer lifespans, and greater numbers of seniors managing their money alone, the pitfalls of personal finance now affect billions of people around the world. Fixed proposes concrete solutions that harness the expertise of economists, the power of government, and the speed of technology to restore fairness and trust in our broken system and make it work better for ordinary people.

Learn more and save 30% with PUP30: https://hubs.ly/Q04t39fL0

13/08/2026

About 40% of global CEOs continue to cite new-business building as one of their top three strategic priorities despite cost pressures.

Here are four focus areas, as well as some of the trade-offs, that leaders may need to make to move fast on new ventures without compromising the parent company’s brand or operations. https://mck.co/4hYmqjO

07/08/2026

The highest form of intelligence, according to some researchers, isn't logic, speed, or memory.

It's metacognition, the ability to think about your own thinking.

Metacognition is the brain watching itself. When you "notice yourself thinking," the spotlight turns inward.
You stop being inside the thought. You start examining it.

Neuroscientists have found that during this kind of self-observation, a region in the anterior prefrontal cortex becomes more active.

In plain terms: you have a neural system specifically designed for self-observation. Your brain can study its own code in real time.

A practical example: simple emotion labeling. Saying "I'm anxious" or "I'm angry" changes what the brain is doing. Not metaphorically. Literally.

Research from UCLA suggests that labeling an emotion engages regulatory regions in the prefrontal cortex and dampens activity in the amygdala, the brain's alarm system.

Naming your inner state shifts brain activity.
Awareness itself can alter the pattern.

While metacognition is the ability to think about your own thinking, memory reconsolidation is the ability to recall and edit your own memories.

When you recall an event, the memory becomes temporarily malleable.
For a short window, new context or emotional meaning can be added.
You're not erasing the past.
You're updating how it's stored and remembered.

That is metacognition applied to past experiences.

This is the exact reason reason why some forms of therapy work.
It changes the meaning attached to remembered experience.
The memory stays. The grip it has on you loosens.

Put it together and the picture is striking:
→ You can observe your own thinking.
→ Naming a feeling shifts your brain.
→ Recalling a memory makes it editable.

You are not stuck with your default reactions. You have leverage on them, if you notice them.

So the next time you catch yourself saying:
"Wait, why did I react like that?"
That moment is not trivial.
It's metacognition at work.
And it's often the first step in rewriting what you do next.

We spend our lives inside our thoughts. That single move, noticing instead of reacting, is the difference between living on autopilot and living on purpose.

Your brain is already equipped for it. All you have to do is use it.

Fleming, S. M., & Dolan, R. J. (2012). The neural basis of metacognitive ability. *Philosophical Transactions of the Royal Society (1594), 1338-1349.
https://pmc.ncbi.nlm.nih.gov/articles/PMC3318765/

Lieberman, M. D., Eisenberger, N. I., Crockett, M. J., Tom, S. M., Pfeifer, J. H., & Way, B. M. (2007). Putting feelings into words: Affect labeling disrupts amygdala activity in response to affective stimuli, 421-428.
https://sanlab.psych.ucla.edu/wp-content/uploads/sites/31/2015/05/Lieberman_AL-2007.pdf

Nader, K., Schafe, G. E., & LeDoux, J. E. (2000). Fear memories require protein synthesis in the amygdala for reconsolidation after retrieval. (6797), 722-726.
https://www.nature.com/articles/35021052

06/08/2026

Marzyeh Ghassemi, the Germeshausen Career Development Professor at MIT in the Department of Electrical Engineering and Computer Science and the Institute for Medical Engineering and Science (IMES), is a finalist in the MIT-Royalty Pharma Faculty Founder Initiative prize competition, which supports biotech innovators and faculty entrepreneurs interested in commercializing their solutions.

Ghassemi is creating a new layer of data-centric safety infrastructure that helps ensure AI systems remain reliable in high-stakes settings such as healthcare, finance, and public services by identifying out-of-distribution or corrupted inputs before they reach a model.

https://news.mit.edu/2026/mit-royalty-pharma-faculty-founder-initiative-supports-biotech-innovators-0227

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