SciBerg

24/10/2018

We are proud to contribute to the research article published in Scientific Reports this year:

https://www.nature.com/articles/s41598-018-20215-5

This study addressed the analysis of the entire network of gene-gene interactions mediated by intragenic miRNAs and identified the network core consisting of genes mutually connected via their intragenic miRNAs. Interestingly, genes forming the core were involved in key cellular processes, including DNA replication, transcription, protein homeostasis and cell metabolism. The described network core, consisting of genes mutually regulated by their intragenic miRNAs, could coordinate adjacent pathways or homeostatic control circuits, serving as a horizontal inter-circuit link. Notably, expression patterns of these genes had an efficient prognostic potential for breast and colorectal cancer patients

Article

23/09/2018

Our recent contribution to Frontiers in Physiology.
The state-of-the-art in the field of early diagnosis of NAFLD using circulating miRNAs:

Nonalcoholic fatty liver disease (NAFLD) is the worldwide most common cause of chronic liver pathology, which prevalence strongly correlates with the increasing incidence of diabetes, obesity and meta-bolic syndrome in the general population. Simple steatosis, the earliest NAFLD stage, usually remai...

26/06/2018

Our recent contribution to the publication in BMC Cancer:

https://bmccancer.biomedcentral.com/articles/10.1186/s12885-017-3915-z

This article describes the experimental design and the protocol for the upcoming study to be conducted by several collaboration partners, including German Cancer Research Center, University of the Witwatersrand (South Africa), National Cancer Institute (USA) and SciBerg e.Kfm. The aims of this proposed study is identification of circulating miRNAs biomarkers for hepatocellular carcinoma (HCC) in a setting with high HIV/HBV co-infection. We foresee that HCC specific blood-based miRNA biomarkers will be useful for early diagnosing of HCC as well as predicting the clinical course and/or therapeutic response to chemotherapy.

A wide range of studies has investigated the diagnostic proficiency of extracellular microRNAs (miRNAs) in hepatocellular cancer (HCC). HCC is expected to increase in Sub-Saharan Africa (SSA), due to endemic levels of viral infection (HBV/HIV), ageing and changing lifestyles. This unique aetiologica...

28/02/2018

NEW: A quick conversion of your FASTQ files from any RNA-seq experiment into ready-to-work-with count matrices:
https://sciberg.com/services/fastq_to_counts.html

02/09/2017

SciBerg is a newly established company, located near Heidelberg (Germany), providing R&D consulting, experimental design and bioinformatics support for research projects which involve Next-Generation Sequencing (Massive Parallel Sequencing, Deep Sequencing), qPCR and Microarray technologies. We integrate a group of qualified Ph.D holding scientists with a profound technological expertise in the above methods and substantial experience in the corresponding data analysis. Our specialists have an in-depth understanding of current bioinformatics concepts combined with the ability to think "outside the box". We provide solutions and services which can be fully customized depending on your project requirements.

06/06/2017

We are online! www.sciberg.com