02/09/2026
๐ ๐ฃ๐๐ฏ๐น๐ถ๐ฐ๐ฎ๐๐ถ๐ผ๐ป ๐๐ฝ๐ผ๐๐น๐ถ๐ด๐ต๐: ๐ง๐ฎ๐ฟ๐ด๐ฒ๐๐ฒ๐ฑ ๐ฝ๐ฟ๐ผ๐๐ฒ๐ผ๐บ๐ถ๐ฐ๐ ๐๐๐ฝ๐ฝ๐ผ๐ฟ๐๐ถ๐ป๐ด ๐๐น๐ผ๐๐ต๐ผ ๐ฟ๐ฒ๐๐ฒ๐ฎ๐ฟ๐ฐ๐ต (๐ฎ๐ฌ๐ฎ๐ญ)
In 2021, a study published in Scientific Reports investigated expression of the longevity-associated protein ฮฑ-Klotho in the naked mole rat, a species known for its exceptional lifespan.
Because no specific antibodies exist for detecting Klotho in this model, the researchers applied targeted proteomics using Parallel Reaction Monitoring (PRM) to measure Klotho protein expression in kidney and liver tissue.
At Biogenity, we performed the PRM-based proteomics analysis, using high-resolution mass spectrometry to detect Klotho-derived peptides in complex tissue samples.
We enjoy looking back at studies like this, where targeted mass spectrometry enables protein-level measurements when conventional approaches are not available.
๐ https://doi.org/10.1038/s41598-021-94972-1