Neuroservices-Alliance

Neuroservices-Alliance: the CNS & Pain Electrophyisiology CRO.

03/09/2026

Epileptiform discharges appear in the EEG of 90% of patients with epilepsy.

We can record the same electrical signature in vitro, in a hippocampal brain slice, on a Multi-Electrode Array.

That's the foundation of our antiepileptic drug profiling platform.

The readouts are quantitative: epileptiform discharge rate, discharge amplitude, population spike area under the curve, measured in real time, across dozens of electrodes simultaneously.

Our assays gives you human-translatable, mechanistically grounded functional data.

Discuss with our scientists your epilepsy study plan:

🔗 neuroservices-alliance.com/contact

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31/08/2026

Neuroservices-Alliance × FUJIFILM Cellular Dynamics — officially partners.

iPSC-derived neurons are at the forefront of New Approach Methodologies in CNS drug discovery.
As regulators and funders alike — including the NIH and FDA — push for more human-relevant, translational models, the shift away from purely animal-based testing is accelerating. iPSC neurons are leading that shift. ✅

This partnership brings together FUJIFILM Cellular Dynamics' gold-standard human iPSC-derived cell technology and Neuroservices-Alliance gold standard in vitro electrophysiology recordings. The result is an integrated offering — better cell models, paired with state-of-the-art functional assays.

If your program needs human-relevant CNS data, we're ready.

🔗 Read more → https://www.neuroservices-alliance.com/neuroservices-alliance-partners-with-fujifilm-cellular-dynami...

31/08/2026

🧠 The brain is our specialty — in all its complexity.

At Neuroservices-Alliance, our electrophysiology platforms support preclinical drug discovery across CNS and pain therapeutic areas — from the most established targets to the ones the field is only beginning to understand.

Whatever your program targets, we co-design the study around your scientific question.

🔗 neuroservices-alliance.com/therapeutic-areas

31/08/2026

🔬 Most scientists don't walk into their first meeting with us knowing exactly what they need.

That's why our introductory meetings aren't sales calls. They're scientific conversations where we listen to your program, your constraints, and your question. By the end of our meeting, you'll know why electrophysiology is the right tool to answer those questions.

If you're looking for answers, let's talk.

🔗 neuroservices-alliance.com/contact

31/08/2026

🧬 Synaptic function is one of the earliest casualties in many neurodegenerative diseases. But measuring it in a human-relevant model — at the synapse level — has historically been a challenge. That's where iPSC Neurons come in.

NSA ran a Patch Clamp study using FUJIFILM CDI's iCell GlutaNeurons to measure mEPSCs — a direct readout of synapse integrity in human iPSC-derived neurons.

This matters for neurodegeneration programs where synapse loss is a key feature and gene silencing therapies need functional validation.

🔗 neuroservices-alliance.com/experts-platform/cell-electrophysiology

31/08/2026

🔬 Every spike tells a story.

The question is which story does your program need to hear?

A rodent primary neuron tells you about membrane properties. It's the story of the cell itself.

A DRG sensory neuron tells you about the target. It's the story of where therapeutics need to act.

A brain slice tells you about the native network. It's the story of how neurons actually talk to each other.

A human iPSC cell tells you about human biology. It's the story that translates.

At Neuroservices-Alliance, we don't ask you to choose just one. We help you decide which combination of models, techniques, and readouts gives your program the most complete answer.

🔗 www.neuroservices-alliance.com

31/08/2026

🧠 What you're looking at: brain slices, the starting point of the electrophysiology studies we run.

For over 20 years, our Brain Slice Lab has been the reference for in vitro slice electrophysiology in CNS and pain drug discovery.

If your program needs functional data from tissue that reflects real brain biology, this is where it starts.

🔗 neuroservices-alliance.com/experts-platform/brain-slice-electrophysiology

31/08/2026

🧠 Twenty years of neuroscience. Still curious.

From our Brain Slice Lab in Aix-en-Provence to our Cell Lab in San Diego, we remain what we've always been , a team of neuroscientists who believe that the right data, generated the right way, can change the course of a drug discovery program.

Explore our expert platforms:

https://www.neuroservices-alliance.com/our-experts-platforms/

31/08/2026

Behind every study is a team of multidisciplinary neuroscientists who interpret what they see, challenge the data, and make sure the results mean something for your program.

We believe science is a conversation. You'll have direct access to the scientists working on your project, where you can expect updates when things are interesting and transparency when something needs to be discussed.

That's how we've built 300+ client partnerships over 20 years. Not just on expertise, but on trust.

🔗 neuroservices-alliance.com/contact

31/08/2026

Not all iPSC-derived neurons mature on the same clock. ⏱️

We tracked mEPSCs in iCell Glutamatergic and Motor neurons from week 2 to week 8, mapping exactly when synaptic activity becomes assay-ready for each. Part of how we're building out human iPSC-based cell electrophysiology to support NAMs with reproducible, human-relevant data.

Full data breakdown 👇

https://www.neuroservices-alliance.com/mini-epscs-in-human-ipsc-derived-neurons-maturation-profiling...

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