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Goss Scientific Instruments Ltd Goss Scientific Instruments supply products and services to the Stable Isotope, NMR and Mass-spec communities as well as quantum technology manufacturers.

www.ukisotope.com

Supplier of Cambridge Isotope Laboratories Inc. products in the UK

Could mass spectrometry help detect illicit drug residues in real-world environments? 🔬A newly published study in the Jo...
16/10/2026

Could mass spectrometry help detect illicit drug residues in real-world environments? 🔬

A newly published study in the Journal of Mass Spectrometry by researchers from University of Surrey explores an intriguing application of analytical science: screening for illicit drug residues on surfaces in a UK pub using atmospheric solids analysis probe mass spectrometry (ASAP-MS).

The research team collected more than 400 surface swabs over three weeks, sampling common touchpoints including tables, the bar and bathroom surfaces. The study investigated the detection of co***ne, ketamine, amphetamine, diazepam and THC.

🔍 What did the researchers find?

• Drug residues were detected across all sampled touchpoint areas, with bathroom samples showing particularly notable findings, including co***ne traces in every bathroom sample analysed.

• Targeted ASAP-MS analysis with minimal sample preparation detected trace amounts that had been missed during initial screening.

• Direct, untargeted analysis showed potential for detecting larger quantities of certain substances, particularly co***ne.

• Liquid chromatography–mass spectrometry (LC–MS) was used for confirmatory analysis, highlighting the importance of combining rapid screening with established analytical methods.

💡 Why does this matter?
Ambient ionisation mass spectrometry offers the potential for rapid analysis with minimal sample preparation. Developing these approaches could support future applications in forensic investigations, environmental screening and public health research, where timely information outside traditional laboratory settings is valuable.

An important caveat: detecting drug residues on a surface does not establish who deposited them, when they were deposited, or whether anyone experienced harmful exposure. These findings demonstrate analytical potential, not proof of drug use or risk to individual patrons.

This study is a compelling example of how analytical chemistry can move beyond the laboratory to investigate complex, real-world environments.

📄 Read the full open-access article:
https://doi.org/10.1002/jms.70121

💡 Can UV LEDs make photodissociation mass spectrometry more accessible?A new study by Department of Chemistry, Universit...
09/10/2026

💡 Can UV LEDs make photodissociation mass spectrometry more accessible?

A new study by Department of Chemistry, University of York, UK demonstrates ultraviolet photodissociation (UVPD) using UV LEDs externally interfaced with a linear ion-trap mass spectrometer — offering a potential alternative to the high-power lasers traditionally used for this technique.

🔬 The researchers demonstrated photodissociation at 280 and 365 nm using model compounds, including flavin mononucleotide, tryptophan and leucine enkephalin.

🚀 By replacing complex laser systems with compact, lower-cost LEDs, this approach could help make UVPD more accessible. Although longer irradiation times are currently required, the results provide an exciting proof of concept for simpler UVPD instrumentation.

A great example of how innovative light-source technology could open new possibilities in mass spectrometry!

Full Article Here https://doi.org/10.1021/jasms.6c00354

Could mass spectrometry help surgeons see where a brain tumour ends — in just three minutes?Researchers from Purdue Univ...
02/10/2026

Could mass spectrometry help surgeons see where a brain tumour ends — in just three minutes?

Researchers from Purdue University and Mayo Clinic have developed a rapid mass spectrometry approach for assessing glioma tissue and tumour margins. Using syringe touch-spray ambient ionisation tandem mass spectrometry, the team can measure molecular signatures in a tissue sample in roughly three minutes.

The approach looks at ratios of endogenous metabolites and, in a study of 86 human brain samples, was able to distinguish glioma from non-tumour tissue, while also providing information about tumour subtype and mutation status. The potential significance is that molecular information could become available on the timescale of surgery, rather than relying solely on conventional pathology performed afterwards.

A few key takeaways:

• ⏱️ ~3-minute analysis — potentially compatible with the timeframe of brain surgery

🧬 Molecular information — metabolite signatures can distinguish tumour from non-tumour tissue

🎯 Margin assessment — could help identify infiltrating tumour cells at difficult-to-assess boundaries

🔬 More than diagnosis — the method also showed potential for tumour subtype and mutation-status classification

🏥 Clinically focused technology — the team is now looking towards further intraoperative studies and eventual clinical trials

🤝 Analytical science meets surgery — a great example of mass spectrometry moving beyond the laboratory and towards real-time clinical decision support

Importantly, the researchers emphasise that this technology is not intended to replace the current standard of care, but could provide surgeons with additional molecular information that is currently unavailable during the operation.

A fascinating example of how advances in ambient ionisation MS, rapid sampling and molecular profiling could expand the role of mass spectrometry in clinical medicine.

🌱 Redefining resource efficiency in semiconductor manufacturingKanken Techno Co., Ltd. has achieved a significant miles...
24/09/2026

🌱 Redefining resource efficiency in semiconductor manufacturing

Kanken Techno Co., Ltd. has achieved a significant milestone in semiconductor sustainability: the development of the world’s first on-site neon (Ne) gas recycling system for excimer lasers used in semiconductor lithography.

Why does this matter?

Excimer lasers are critical to advanced semiconductor manufacturing, and neon is an essential — and costly — component of their laser gas. Kanken Techno’s technology enables the gas to be recycled directly at the fab, reducing both resource consumption and environmental impact.

The results are particularly impressive:

🔹 Over 90% neon gas recycling rate
🔹 A single recycler can support up to five high-usage excimer lasers
🔹 The system removes impurities including H₂O, O₂ and CF₄
🔹 Integrated Quadrupole Mass Spectrometry (QMS) enables precise gas analysis and control
🔹 The injection portion of gas supply — representing more than 90% of laser gas usage — can achieve 100% effective recycling

Importantly, the system is already operating at a semiconductor fab, with one recycler connected to three ArF excimer lasers and continuously recycling process gas.

This is a strong example of how semiconductor sustainability is moving beyond energy efficiency and emissions reduction toward genuine resource circularity.

As semiconductor manufacturing continues to scale, technologies that reduce the consumption of critical process gases while maintaining production performance will become increasingly important.

Congratulations to the Kanken Techno team on this important achievement. 👏

⚛️ 🔬 Quantum sensing is moving another step closer to the field.A new development from Johns Hopkins Applied Physics Lab...
18/09/2026

⚛️ 🔬 Quantum sensing is moving another step closer to the field.

A new development from Johns Hopkins Applied Physics Laboratory (APL) is exploring a portable quantum sensing platform that could bring the capabilities of nuclear magnetic resonance (NMR) spectroscopy into environments where conventional systems are simply too large and complex.

🎯 The goal? A device roughly the size of a laptop that could help identify both chemical and biological threats from very small samples.

💎 What makes the approach particularly interesting is the use of nitrogen-vacancy (NV) centers in diamond combined with specially designed nano-containers to confine nuclear spins. Simulations suggest this could significantly improve signal sensitivity, potentially enabling detection from extremely small sample volumes.

The bigger story here isn't just the sensor itself. It's the convergence of:

🔹 Quantum sensing
🔹 NMR spectroscopy
🔹 Microfluidics
🔹 Microfabrication
🔹 Chemistry and physics

Together, these disciplines could turn a traditionally laboratory-based analytical technique into something much more practical for field environments.

And the potential applications may extend well beyond chemical and biological threat detection — including environmental monitoring, GPS-denied navigation and other sensing challenges.

This is a good example of where the real value of quantum technologies may emerge: not necessarily from replacing classical systems outright, but from enabling capabilities that were previously difficult or impractical to deploy.

The technology is still at the prototype and validation stage, but it is an intriguing example of quantum sensing being engineered around a real-world mission requirement.

📖 🔬 Pushing the limits of single-cell proteomics to investigate bacterial heterogeneity using bacSCP.Firstly, everyone f...
11/09/2026

📖 🔬 Pushing the limits of single-cell proteomics to investigate bacterial heterogeneity using bacSCP.

Firstly, everyone from Goss Scientific Instruments Ltd had a fantastic time at the British Mass Spectrometry Society - BMSS annual meeting. It was an absolute pleasure chatting with so many of you.

To follow on from the event, our latest blog post is an exciting review of breakthroughs made in bacteria Single-Cell Proteomics (SCP) by mass spectrometry (MS): an emerging analytical approach that continuously pushes the limits of technology towards improved reproducibility, throughput and sensitivity. These exciting new developments were brought to you by researchers from Research Institute of Molecular Pathology (IMP), Vienna.

Follow the link below to read more about the successful downscaling of proteomic workflows and integrating SCP for understanding bacterial heterogeneity.

https://www.ukisotope.com/pushing-the-limits-of-single-cell-proteomics-to-investigate-bacterial-heterogeneity-using-bacscp/

📅 This coming Friday is the 44th Congress of the The European Society of Cataract and Refractive Surgeons (ESCRS). 🧑‍🔬👁️...
07/09/2026

📅 This coming Friday is the 44th Congress of the The European Society of Cataract and Refractive Surgeons (ESCRS).

🧑‍🔬👁️ An exceptional gathering of brilliant minds from the field of Ophthalmology. The ESCRS Congress will feature Main and Research Symposia, Arena Debates, The Global Refractive Symposium, 3D Surgical Microscope and AI Summit, ESCRS/EURETINA Symposium, Near Live Surgery, Instructional Courses, Wetlabs, Video Sessions, Posters and Oral Presentations as well as various other special interest days and sessions, such as the ESCRS iNovation® Day.

🤝 Unfortunately, due to scheduling conflicts, our UK contingency of gas experts from Goss Scientific Instruments Ltd will be unable to attend this year.

However, we are very excited to have our partners from the BUSE GROUP visiting from Germany/Netherlands. Fabian Richrath, manager of Excimer Laser Gases for the BUSE GROUP will be there; networking with the many Excimer Laser Gas users also in attendance.

Excimer Lasers are one of the foremost technologies when it comes to ophthalmic surgeries. The primary gas used to create the powerful, low ablation laser is Argon Fluoride (193 nm); and thanks to our partners at the BUSE GROUP we have access to a variety of laser gases and are the UK's leading supplier of ultra-high purity gases for Excimer Laser applications.

📅 8th - 10th September 2026 the 46th British Mass Spectrometry Society - BMSS Annual Meeting will be taking place at the...
04/09/2026

📅 8th - 10th September 2026 the 46th British Mass Spectrometry Society - BMSS Annual Meeting will be taking place at the Royal Armouries Museum in Leeds, UK.

Goss Scientific Instruments Ltd are proudly sponsoring the event and will be in attendance to showcase what we have to offer.

We are the leading UK supplier of Cambridge Isotope Laboratories, Inc products, including; Deuterated Solvents, Mass Spec Standards, Metabolite Mixtures & Kits, Reagents and more.

Please stop by and say hello to our dedicated representatives who will be more than happy to discuss what we do. There will likely be a small mountain of freebies to takeaway too, such as pens, notepads, mugs etc. Feel free to help yourselves.

📅 Goss Scientific are sponsoring this years Meeting of Inorganic Chemists Recently Appointed (MICRA) event at the Yusuf ...
03/09/2026

📅 Goss Scientific are sponsoring this years Meeting of Inorganic Chemists Recently Appointed (MICRA) event at the Yusuf Hamied Department of Chemistry, University of Cambridge.

Not only are we helping sponsor the event, but we will also be in attendance exhibiting all the products and services we have to offer. If you are an early career chemist feel free to stop by our stall. Jonathan Bell will be more than happy to discuss everything we do and will likely have a smörgåsbord of promotional merch for you to take away, absolutely FREE!

🚨 Limited Time Offer 🚨 Up to 70% Off — While Stock LastsCambridge Isotope Laboratories, Inc are having a clearance sale....
03/09/2026

🚨 Limited Time Offer 🚨 Up to 70% Off — While Stock Lasts

Cambridge Isotope Laboratories, Inc are having a clearance sale. Select batches are nearing the end of their shelf life. Same quality, same products — just priced to move before they expire.

For a full extensive list of reduced products visit the following link:

https://isotope.com/special-offers/

Contact Goss Scientific Instruments Ltd and we will ensure you get the best prices possible.

Phone: (+44) 01270 580888
Email: [email protected]
Website: www.ukisotope.com

Address

Unit 5, Alexandra Business Park
Crewe
CW25DD

Opening Hours

Monday 9am - 4:30pm
Tuesday 9am - 4:30pm
Wednesday 9am - 4:30pm
Thursday 9am - 4:30pm
Friday 9am - 4pm

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