15/09/2026
How Circadian Rhythm Affects Diagnostic Test Results
➡️ Circadian rhythm is the body’s natural ~24-hour biological cycle that influences hormones, metabolism, sleep and other physiological functions.
➡️ Some biomarkers show predictable variations throughout the day.
➡️ Cortisol is typically highest in the morning and decreases throughout the day.
➡️ TSH generally shows a circadian pattern, with levels tending to rise during the night.
➡️ Testosterone is generally higher in the morning, particularly in younger men.
➡️ Always interpret time-sensitive results according to the specific test, collection protocol and laboratory reference interval.
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