Human Molecular Genetics Laboratory, RGCB

10/04/2023

Spent some great time in BANGALORE BIOINNOVATION CENTRES (BBC) and CENTRE for HUMAN GENETICS in Bengaluru. Meeting and interacting with Prof Sharat Chandra, Prof HA Ranganath and Prof Nanjundaih was indeed very exciting. Good to see all in very active and healthy state, still keeping updated with recent developments. Presence of such professors will motivate youngsters to take science seriously, this was evident while interacting with students of CHG. In BBC, each room was a incubation company, churning out products and businesses out of their innovative ideas and Jugaadu methods.

22/03/2022

Congratulations swathy for your new article. Her study hints for a cautionary note for investigators who pick up observations from reported literature for altered miRNA involved in pathogenesis and investigate its biological implications. She identifies several miRNAs to be differentially expressed impacting the pharmacokinetic, pharmacodynamics, and epigenomics properties of antipsychotic drug treatment. Interestingly, some of these miRNA expression patterns were similar to reported miRNA observations on schizophrenia pathogenesis. This study unravels the potential role of miRNAs in the mechanism of action of the antipsychotic drug and could also reflect in drug-induced side effects. This study also signifies the importance of pharmacoepigenomics approach while evaluating the role of miRNAs in pathogenesis.
Frontiers in Molecular Neuroscience, 22 March 2022
https://www.frontiersin.org/articles/10.3389/fnmol.2022.786632/

14/01/2022

https://www.facebook.com/1626554440890822/posts/2946738412205745/

Pharmacogenomics VOL. 23, NO. 2 | Editorial normal Pharmacoepigenomics: a key determinant in resolving epigenomic parameters in pathogenesis and treatment response in complex diseases Moinak Banerjee Moinak BanerjeeMoinak Banerjee *Author for correspondence: Tel.: +91 471 252 9529; E-mail Address: m...

10/09/2021

08/04/2020

Sharing my article published in Economic Times on my opinion for a long term solution for all infectious disease including COVID19 pandemic. It also talks on budgetary provisions and how minimal we spent on health science in compared to space, defence and energy sectors.

Possibly, environmental variations across latitudes might be the driving force for humans to evolve particularly for the immunological genes, in order to adapt or defend the environment or the pathogenic response.

08/04/2020

Once again demonstrating that methylation map gene are critical for determing host epigenomic architechture in various complex disease. "Methylation map genes can be critical in determining the methylome of intracranial aneurysm patients" | Epigenomics https://t.co/SpdcDaMkUC

Aim: Intracranial aneurysm is often asymptomatic until the time of rupture. Elevated homocysteine is reported in vascular diseases. Identifying early events in homocysteine metabolism through methy...

24/01/2020

https://www.nature.com/articles/s41562-019-0802-4

Modern culture appears to change at a rapid rate compared with biological evolution. Lambert et al. test this and find that the pace of modern cultural evolution is surprisingly slow—slower than, for example, changes seen in Darwin’s finches.

21/02/2019

More than Epigenetics it is the genetics of Epigenome that is crucial to understand in disease outcome

IUBMB Life is the flagship journal of the International Union of Biochemistry and Molecular Biology and is devoted to the rapid publication of the most novel and significant short articles, reviews and papers in the broadly defined fields of biochemistry, molecular biology, cell biology, and molecul...

01/01/2019

Wish you all a very happy New year 2019. Human molecular genetics lab party at home.

15/07/2018

http://www.rgcb.res.in/temporaryposition2-13-07-2018.php

The Rajiv Gandhi Centre for Biotechnology (RGCB) is a growing phenomenon. Located in Thiruvananthapuram, the capital city of Kerala, RGCB began in 1990 amongst humble surroundings as a small charitable society called the Centre for Development of Education, Science and Technology (C-DEST). In 1991,....

15/07/2018

Applications are invited from suitable candidates for one position of Junior Research Fellow

The Rajiv Gandhi Centre for Biotechnology (RGCB) is a growing phenomenon. Located in Thiruvananthapuram, the capital city of Kerala, RGCB began in 1990 amongst humble surroundings as a small charitable society called the Centre for Development of Education, Science and Technology (C-DEST). In 1991,....