Cell Handler2

Name: Cell Handler2
Address: 中央区豊岡町 127, Hamamatsu-shi, Shizuoka, 4338103, JP
Telephone: +81535257292

CELL HANDLER™2 is a precise cell picking and imaging system designed to streamline complex workflows and support innovative drug discovery research.

It aims to contribute to the advancement of drug discovery.

26/08/2026

Manual spheroid transfer may seem like a simple step, but it can become a bottleneck when throughput and reproducibility are critical.

In one of our application studies using HT-29-derived spheroids, CELL HANDLER™ demonstrated greater efficiency in spheroid transfer compared with a conventional manual method, including:

⏱️ Approximately 60% reduction in operation time
💧 Approximately 99% reduction in carry-over medium
✓ Cell transfer success and morphology retention rates equal to or higher than those achieved with manual transfer

For researchers working with spheroid-based assays or microphysiological systems (MPS), reducing variability during sample transfer can help create more consistent, efficient, and reproducible workflows.

See how automated spheroid transfer can support your research:

https://global.yamaha-motor.com/business/hc/case/application/?utm_source=LinkedIn&utm_medium=social&utm_campaign=LinkedIn_APN

19/08/2026

Mark your calendar and register today! During the 32nd TMiMS International Symposium in October 2026, Yamaha Motor will present “Efficient Isolation of Tetraploid Human iPSC Clones by CELL HANDLER™2: An Image-Based Automated Cell-Picking Technology.”

Under the theme “Polyploidy in Evolution, Development, and Disease,” the symposium will bring together researchers in and outside Japan to discuss the latest findings in polyploidy research, spanning basic life sciences to medicine.

In the presentation, you will learn how Yamaha technologies can support researchers in isolating tetraploid human iPSC clones in an efficient and traceable manner. Registration is open through August 31, 2026.

📅 October 13–15, 2026
📍 Tokyo Metropolitan Institute of Medical Science, Tokyo, Japan
📝 Registration deadline: August 31, 2026

Learn more and register here:
https://www.igakuken.or.jp/public/international/in-sympo32.html

We hope to see you there!

04/08/2026

“How is the CELL HANDLER™ different from conventional pipetting systems?” This was one of the questions we received during a recent scientific meeting.

A part of the answer lies in the Yamaha Precision Tip — a proprietary dispensing tip developed by Yamaha Motor – with a unique plunger design.

Unlike conventional air-displacement pipetting systems, the Precision Tip and its inner plunger allow fine control of aspiration and dispensing across a wide range of sample types and culture environment, from liquid media to semi-solid gel matrices.

The Precision Tip is designed to help researchers:
✔ Minimize air bubbles during dispensing
✔ Place cells with high precision
✔ Aspirate samples directly from gel matrices
✔ Handle precious cells, spheroids, and organoids with minimal physical stress
✔ Fine-tune aspiration and dispensing speed and volume for each application

In cell handling, every transfer matters.
The Precision Tip gives researchers greater control, reproducibility, and confidence in their workflows.

Learn more about the technology behind CELL HANDLER™:
https://global.yamaha-motor.com/business/hc/product/about/

28/07/2026

Can you maintain monoclonality and traceability while improving the efficiency of cell line development? The answer is YES!

At this year's annual meeting of the Japanese Society for Animal Cell Technology (JAACT), Dr. Noriko Yamano-Adachi of Osaka University will present their work on establishing novel cell lines using CELL HANDLER™2.

The seminar will highlight:

• Efficient clone selection using dual-fluorescence imaging
• Monoclonality assurance through image-based cell tracking
• Data traceability throughout the cloning process
• Efficiency improvement potential of cell line development workflows

If you are working on cell line development, cell therapy, or biopharmaceutical manufacturing, join us to explore how image-based automation can enhance both efficiency and confidence in clone selection.

15/07/2026

In antibody discovery and cell line development (CLD), researchers are increasingly seeking workflows that can identify high-value clones efficiently while maintaining confidence in selection decisions.

Through its image-based cell handling technologies, the CELL HANDLER™2 achieves;
🔹 Identification and detection of antibody-producing cells,
🔹 Automated clone picking from target cell populations, and
🔹 Integrated image and data management for traceable decision-making.

These functionalities are helping researchers increase the efficiency and reproducibility of given processes and giving them confidence in their clone selection.

At a technical seminar at JAACT 2026, Dr. Noriko Yamano-Adachi of Osaka University will present the cell line establishment workflow using the CELL HANDLER™2.

Visit us at JAACT to explore how image-based automation can support your cell development workflows.

30/06/2026

Common challenges in toxicity studies that can affect assay quality and data consistency:
* variability in organoid morphology and size
* difficulty in recognizing complex structures
* well-to-well variability, and
* difficulty in tracking changes over time.
That’s where Yamaha’s lab automation solution can help.

Using image-based analysis, the CELL HANDLER™2 can:
• Select organoids based on morphology
• Standardize organoid sizes across wells
• Recognize organoids with complex structures
• Acquire images of organoids in the same wells over time

The CELL HANDLER™2 also supports workflows spanning from genome editing to organoid generation and evaluation.

At the Yamaha Motor booth at the Annual Meeting of the Japanese Society of Toxicology, we will introduce how CELL HANDLER™2 can support research workflows involving respiratory and intestinal organoids.

Please stop by Booth 123, and let’s have a conversation about how Yamaha Motor’s technology could take your toxicity research workflows to the next level.

24/06/2026

Yamaha Motor will be at the ISSCR 2026 Annual Meeting in Montréal, Canada.

Join us at Booth #205 to learn how the CELL HANDLER™2 can help you minimize variability and maximize the efficiency in your lab workflow. We look forward to sharing:
- The instrument’s imaging-based workflow
- AI-based detection models for improved target identification and selection
- Applications in in-vitro models and cell-based assays using organoids and spheroids
- Integration with robot arms and lab instruments
- And MORE!

📅 July 8–11, 2026
📌 Palais des congrès de Montréal, Montréal, Canada
🔹 Booth No.: 205

Our application notes:
https://global.yamaha-motor.com/business/hc/case/application/?utm_source=LinkedIn&utm_medium=social&utm_campaign=LinkedIn_APN

We look forward to seeing you in Montréal!

19/06/2026

What if researchers could better understand disease mechanisms by recreating them at the cellular level?

In our latest User’s Voice article, Dr. Yuichiro Miyaoka of the Tokyo Metropolitan Institute of Medical Science shares how his team uses human iPS cells and genome-editing technology to study disease models.

A key challenge in this field is identifying and isolating the right cell clones. Dr. Miyaoka explains how CELL HANDLER™ supports his team by isolating target iPS cell clones in a 3D gel culture environment, enabling them to visually identify, select, and recover the clones needed for downstream evaluation.

Read the full story to learn how automated cell picking can support iPSC-based disease modeling and regenerative medicine research:

https://global.yamaha-motor.com/business/hc/case/voice/002/

17/06/2026

Yamaha Motor will be at the 53rd Annual Meeting of the Japanese Society of Toxicology.

Join us at Booth #123 to learn how the CELL HANDLER™2 can help you minimize variability and maximize the efficiency in your lab workflow. We look forward to sharing:
✔ The instrument’s imaging-based workflow
✔ AI-based detection models for improved target identification and selection
✔ Applications in in-vitro models and cell-based assays using organoids and spheroids
✔ Integration with robot arms and lab instruments
✔ And MORE!

📅 July 1–3, 2026
📍 Grand Cube Osaka, Japan
📍 Booth #123

12/06/2026

Today, specialized labware such as AggreWell™ and Elplasia® supports advanced drug screening and toxicity testing workflows. While these specialized microplates help optimize cell generation, bottlenecks remain in downstream manual cell handling, limiting throughput and scalability.
Enter CELL HANDLER™2.

Compatible with specialized plates including EZSphere™, CELL HANDLER™2 can transfer 96 target spheroids in just 10 minutes with a near-100% success rate, while maintaining traceability for every transferred cell.

With Yamaha Motor’s lab automation solution, researchers can benefit from:
✔ Reduced manual handling and workflow bottlenecks
✔ Improved reproducibility in downstream processes
✔ Reduced cell damage using Yamaha’s proprietary tips
✔ Flexibility to support various SBS-format plates and culture workflows

Discover more in our Application Notes:
https://global.yamaha-motor.com/business/hc/case/application/?utm_source=LinkedIn&utm_medium=social&utm_campaign=LinkedIn_APN

住所

中央区豊岡町 127
Hamamatsu-shi, Shizuoka
4338103

電話番号

+81535257292

ウェブサイト

https://www.yamaha-motor.co.jp/hc/

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