03/09/2026
Vets got it wrong more often than the owners did.
This is the placebo effect in dogs, except the dog isnât the one being fooled.
Dogs canât form an expectation about a capsule. They donât know theyâve been given anything. And expectation is supposed to be the whole mechanism in humans.
So whatâs actually happening?
Partly itâs us. In 58 dogs on placebo, owners reported their dog was better 39.7% of the time. Vets: 44.8%. Force-plate gait analysis said 46 of those 58 hadnât changed at all. The longer the trial ran, the stronger the effect got.
And partly the dog probably does improve a bit, just not from the capsule. Starting a treatment usually means shorter walks, more rest, a new bed, some weight off, an owner suddenly watching how the dog gets up off the floor. I donât know how much of the 39.7% is that, and Iâm not sure anyone does.
What I do know is that we want our patients to get better. Thatâs why we chose this job. Iâve stood in a consult room and watched a dog cross the floor and thought, yes, definitely better.
Who knows how many times I was actually right.
Is it not interesting how we can trick our minds like this?
The publication: Conzemius & Evans, JAVMA 2012.