07/23/2024
July’s monthly protein feature highlights Activin A!
As a part of the TGF-β superfamily, it plays a role in immune response, wound repair, maintenance, and differentiation. Activin A interacts with SMAD2/3 receptors and regulates self-renewal pathways. Activin A is often associated with immune cells, human embryonic stem cells, and mesenchymal progenitor cells. Because of its role, Activin A has been involved in allergies, autoimmune diseases, and cancers.
Activin A has a half-life of less than 24 hours, which can cause issues in its applications in cell culture. However, by using sustained-release products, the concentration needed to maintain cell cultures can be reduced up to 10x depending on the application. This change increases cell survival and differentiation, all while reducing feeding schedules! Take a look at the StemCultures Activin A products on the website, found at the link in our bio.
Stay tuned for future featured proteins, with VEGF appearing next! DM us for any references, questions, or additional information.
