Don Ryan Center for Innovation

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Don Ryan Center for Innovation The DRC empowers entrepreneurs and small businesses with the resources, support, and connections they need to thrive.

Founded in 2012, the Don Ryan Center for Innovation is a not-for-profit organization dedicated to helping entrepreneurs succeed and innovative companies grow. We provide innovators with the space, the resources, the experienced guidance and the contacts in order to successfully launch, and grow, their business. In today's unprecedented times, and in response to economic challenges facing businesses throughout the Lowcountry produced by the COVID-19 pandemic, the Don Ryan Center for Innovation has been appointed by the Town of Bluffton as the DRCI Small Business Concierge - expanding our mission and serving as a resource clearinghouse of local, state and federal resources. Through the Town of Bluffton's commitment to economic recovery, the DRCI Small Business Concierge was created to enable DRCI to put its resources to work to help local businesses respond to the business disruption being faced today, and provide them with the resources they need to help them plan for recovery.

10/16/2026
Episode 4 of Bald Guys on Business is here!Paul and Evan answer common business questions and bring Matt Holmes of 221B ...
10/06/2026

Episode 4 of Bald Guys on Business is here!

Paul and Evan answer common business questions and bring Matt Holmes of 221B Studios out from behind the camera and into the conversation.

Real questions, practical advice, and plenty of laughs. Check it out!

In Episode 4 of Bald Guys on Business, Paul Arvantides and Evan Wel...

The stats (or facts) speak for themselves. Don Ryan Center-supported companies significantly outperform the typical U.S....
10/05/2026

The stats (or facts) speak for themselves. Don Ryan Center-supported companies significantly outperform the typical U.S. business survival odds. Visit our website to find out why: www.donryancenter.com

We’re proud to be featured in the ’s new Business Resource Guide!The guide is a great resource for anyone looking to sta...
10/01/2026

We’re proud to be featured in the ’s new Business Resource Guide!

The guide is a great resource for anyone looking to start, grow, or do business in Bluffton and it highlights how the Don Ryan Center is here to help businesses succeed. Learn more at https://donryancenter.com

Keep an eye out for your copy around town!

09/25/2026

🇺🇸🌎 LOCAL BUSINESSES - HELP US CELEBRATE HISPANIC HERITAGE MONTH!

We’re inviting businesses throughout the Lowcountry to join us in celebrating the culture, contributions, entrepreneurship, and people who make our community stronger.

Display a Hispanic Heritage Month banner at your business and help us send a simple message: Everyone is welcome here, and our community celebrates together.

Support ALL of our local small businesses. ❤️

Thank you to businesses like Vaden of Beaufort and organizations like the Don Ryan Center for Innovation for joining the celebration!

Want a banner for your business? Let us know!

¡Celebremos juntos! 🎉

Episode 3 of Bald Guys on Business is here!This time, Paul Arvantides and Evan Welsh are talking mentorship. The good, t...
09/23/2026

Episode 3 of Bald Guys on Business is here!

This time, Paul Arvantides and Evan Welsh are talking mentorship. The good, the bad, and why the right mentor can make a huge difference in business.

They’re joined by DRC mentor Jerry Reeves to talk about what makes a great mentor, what entrepreneurs should look for, and why some of the best advice comes from someone who’s already learned a few lessons the hard way.

Good conversation, practical takeaways, and a few laughs along the way. Watch Episode 3: https://youtu.be/B1l82RTm_ik

In Episode 3 of Bald Guys on Business, Paul Arvantides and Evan Wel...

09/22/2026

Are you interested in being a mentor? Support innovation in Bluffton. Become a mentor and share your experiences, guidance, and connections to help local entrepreneurs flourish. Visit our website https://donryancenter.com/mentorship

Address

7 Venture Drive #100
Bluffton, SC
29910

Opening Hours

Monday 8am - 5:30pm
Tuesday 8am - 5:30pm
Wednesday 8am - 5:30pm
Thursday 8am - 5:30pm
Friday 8am - 1pm

Telephone

+18435400405

Website

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