MD Biosciences

04/07/2026

Can s*x differences influence systemic drug exposure?

In a recent MD Biosciences study, female Göttingen minipigs showed higher systemic exposure and delayed peak concentrations following bupivacaine administration.

These findings highlight the importance of characterizing PK variability in translational models when evaluating preclinical safety.

Read the abstract in the comments.

03/25/2026

Most preclinical programs start with strong data.

✔ Target engagement
✔ Rodent efficacy
✔ Acceptable early safety

So why does clinical predictability decline as development progresses?

Many programs encounter the same translational challenges around scale, delivery, durability, and procedural variability.

We mapped where these risks most often emerge so teams can address them earlier while development decisions are still flexible.

Download the Translational Failure Map: https://hubs.la/Q045CnK40

03/17/2026

MEP recordings in our SCI pig model show that immediate post-injury electrophysiology predicts functional recovery, with representative waves captured pre and post-injury.

View poster here: https://hubs.la/Q0453l0F0

02/26/2026

We’re proud to share that MD Biosciences is now accredited by AAALAC International.

AAALAC accreditation is a globally recognized mark of excellence in animal care and goes beyond regulatory compliance.

For our partners, this means:

✔ Independent validation of our animal care program
✔ Stronger study credibility and data reliability
✔ Reduced regulatory risk
✔ Confidence that research is conducted responsibly and ethically

High-quality science starts with high standards.
This milestone reinforces the rigor, responsibility, and excellence we bring to every program.

We’re incredibly proud of our team for reaching this milestone and grateful to the sponsors who trust us with their programs.

02/10/2026

🔍 Advanced AI tools are transforming preclinical wound healing research. DeePathology’s AI-based quantitative histopathology identified and measured key healing markers in a Göttingen minipig burn model.

Download the full posters here, presented at the EWMA conference: https://hubs.la/Q03Vst-y0

01/21/2026

From acute to chronic inflammation, including rheumatoid arthritis and osteoarthritis, our translational models measure immune activation, tissue changes, and therapeutic effects with clinically relevant endpoints. Explore our resources on inflammatory models here:

https://hubs.la/Q03VrcdB0

A range of preclinical inflammatory pain models from acute inflammatory pain to chronic pain associated with arthritic conditions. Preclinical CRO