06/18/2026
The math worked. V37 is officially in the vial.
This means our digital cancer-fighting blueprint can be manufactured into actual physical matter and be tested on actual cancer cells. The attached lab photo is of 4mg of the raw vV37 matter in a vial (a" lyophilized puck")
Our lab partners still have to improve the purity to the 95% level for assays. but the V37 peptide is now an actual thing.
TLDR: Next Step - when we have the 95% purity we need, we ship V37 to our CDMO BioTech lab partners for 'CD and SPR Assays".
Circular Dichroism (CD) is the "Shape Check" to prove the physical drug successfully folded into the perfect spiral-spring key we designed. Surface Plasmon Resonance (SPR) is the "Grip Check" to prove our key actually locks onto the target cancer protein and refuses to let go.
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Full Summary for our fellow bio/tech nerds:
Circular Dichroism (CD) is the "Shape Check". Before we can test V37 against cancer, we have to prove that our physical peptide has actually folded into the correct three-dimensional spiral spring. In the lab, technicians shine a light beam through our dissolved liquid peptide. The way the light bends as it passes through the sample maps out the physical structure, confirming whether the backbone has successfully twisted into the exact 3.6-residue alpha-helical shape required to match our computational blueprint.
Surface Plasmon Resonance (SPR) is the "Grip Check". This is the ultimate test to prove our key actually fits and unlocks MDM2 from p53 in the real world. The lab immobilizes our rogue target cancer protein (MDM2) onto a highly sensitive sensor chip and washes our pure V37 peptide over it. By bouncing a laser off the chip, the machine measures in real-time exactly how fast the key snaps onto the cancer protein and most importantly how long and firmly it grips the target without letting go.
Together, these two trials tell us if our math successfully printed a physical key that perfectly fits the lock and refuses to let go and frees p53. By proving that V37 has the right shape and grip and unlocks MDM2 from p53 means we are one giant step closer to officially unlock the body's natural cancer-killer that forces tumor cells to self-destruct while leaving healthy cells untouched.
https://v37.org/
