Cell Origins

04/09/2024

We are excited to share our latest publication "Improving Pharmacokinetics of Peptides Using Phage Display"!

Our team reviews innovative approaches in phage display for enhancing therapeutic and diagnostic peptides and peptide-conjugated nanoparticles.

Considering pharmacokinetics early on in the drug discovery process paves the way for new therapeutic opportunities but also sets the stage for further innovations in peptide drug development. 🚀

Phage display is a versatile method often used in the discovery of peptides that targets disease-related biomarkers. A major advantage of this technology is the ease and cost efficiency of affinity selection, also known as biopanning, to identify novel peptides. While it is relatively straightforwar...

02/01/2024

Our biotech company Cell Origins, which we founded as three alumni, is in the spotlight in the latest edition of Mizzou Magazine. Chatting about our innovative approach to phage display and using the technology to target cancer cells. I'm excited to have been a part of our dedicated team from day one!

Curious about our technology? Don't hesitate to reach out at our website or to me directly.

A biotech company founded by three MU alumni is dedicated to helping kill cancer cells through phage research.

04/05/2023

We're proud to be featured as this month's member highlight by MOBIO.

The field of phage display has had a major impact on both basic and biomedical research, leading to major advancements that even earned a Nobel Prize in 2018. Jessica Newton-Northup, who has received training from esteemed scientists in the field, is now a part of the team at Cell Origins, which is dedicated to leveraging their vast knowledge and experience to provide vital services like peptide and antibody discovery, screening, and method development.

https://www.mobio.org/

Missouri Biotechnology Association (MOBIO) is the only statewide membership group that speaks with one voice to advance and champion the life sciences in Jefferson City, across the state, and in Washington, D.C. MOBIO represents most extensive and broadest cross-section of life science organizations...

03/28/2023

We're happy to be featured in the Columbia Daily Tribune. The University of Missouri and the city of Columbia, MO played essential roles when we decided to found Cell Origins. We remain deeply connected to the University of Missouri and its commitment to research, innovation, business development, and community collaboration.

We look forward to continuing our work here and impacting research initiatives in the Columbia area.

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Cell Origins uses the pioneering tool phage display developed by MU Nobel Laureate George Smith to discover new drugs.

03/10/2023

As we celebrate Women's History Month at Cell Origins, we find it important to recognize the many women scientists who have contributed to the advancement of phage display technology. The pioneering works of women scientists enabled much of the current applications of phage display technology, while the ongoing efforts of many others are continuing to drive this field forward. Through their hard work and dedication to their scientific research, female scientists have made significant contributions that have helped shape the drug discovery process of today.

Cell Origins provides researchers with critical phage-based laboratory services and kits. We focus on the use of filamentous phage as an inexpensive, reliable, highly stable, and effective replacement for many products currently on the market.

01/24/2023

Phage display technology is a powerful tool used in drug discovery. Here we give a brief overview of the key advantages of phage display in drug discovery.

https://www.cellorigins.com/key-advantages-of-phage-display-in-drug-discovery

11/03/2022

Celebrate Movember with us!

Cell Origins is working to improve the accuracy of data in prostate cancer research by developing a new technology that can identify cell lines and ascertain phenotypic drifting. This is important work that has the potential to advance prostate cancer research to improve the outcomes for patients suffering from this disease. Please contact us if you are interested in beta testing our technology and learning more.

https://www.cellorigins.com/movember-and-prostate-cancer-research

10/31/2022

Cell Origins got started in 2019 when we were awarded an SBIR grant from the NIH to develop a phage-based method to discern the origin of cell lines by measuring genomic, transcriptomic, and phenotypic changes. Thus, we named our company Cell Origins.

https://www.cellorigins.com/cell-origins-pioneers-in-phage-display-technology

Cell Origins provides researchers with critical phage-based laboratory services and kits. We focus on the use of filamentous phage as an inexpensive, reliable, highly stable, and effective replacement for many products currently on the market.

10/29/2022

Phage display is a powerful tool in drug discovery to select peptides with high binding affinity for their target molecule. However, peptides selected against recombinant proteins often have poor pharmacokinetics, which quickly turns a promising lead into a failure.

To overcome this, at Cell Origins we use a multi-tier selection process where we build the desired in vivo behavior of the peptide into the phage display strategy. We work directly with each client to get an in-depth understanding of the biomarker and disease mechanism. This advanced research strategy is worthwhile since the resulting peptide leads have high binding affinity and exhibit excellent pharmacokinetics.

Interested in cutting down on lead generation time? Contact us to learn how we can help. Cell Origins offers custom research strategies and in-house phage display selections by scientists who are leading

cellorigins.com

10/27/2022

Supporting female entrepreneurs is a great way of contributing to the economy and strengthening our local communities.

Here at Cell Origins, we are proud to be a women-owned business that was founded by Mette Soendergaard (Ph.D.), Jessica Newton Northup (M.S.), and LeAnn Kuhlmann Qi (M.B.A) in 2018.

https://www.cellorigins.com/celebrating-womens-business-month-cell-origins

10/21/2022

Biopanning of phage libraries is the most common method of selecting and identifying peptides and antibodies that bind to a target antigen. A traditional biopanning procedure includes the incubation of a phage library with the target of interest followed by the collection of bound phages by elution. Learn more here.
https://www.cellorigins.com/biopanning
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10/20/2022

We are announcing our partnership with RayzeBio to develop targeted radiopharmaceuticals. Cell Origins specialized in using multiple tiers of phage display to find high affinity ligands.

https://cellorigins.prowly.com/210887-cell-origins-partners-with-rayzebio-to-develop-targeted-radiopharmaceuticals?preview=true



Image: Photo by National Cancer Institute on Unsplash