Precision BioSciences

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Precision BioSciences has commenced dosing in the Phase 1/2 FUNCTION‑DMD study, with the first patient receiving PBGENE‑...
08/31/2026

Precision BioSciences has commenced dosing in the Phase 1/2 FUNCTION‑DMD study, with the first patient receiving PBGENE‑DMD at Arkansas Children’s Hospital.

This milestone marks the first clinical gene‑editing program for Duchenne muscular dystrophy and advances our wholly owned in vivo gene editing approach into the clinic.

PBGENE‑DMD is designed to permanently edit a patient’s own dystrophin gene, with the aim of restoring production of a near full‑length, functional dystrophin protein. The study is enrolling ambulatory boys ages 2–7 with mutations between exons 45 and 55, a key hotspot region representing up to 60% of boys living with Duchenne.

The Precision team is grateful to the patient, their family, and the clinical team for their commitment to advancing this important work. Initial safety data are expected by year-end 2026.

Read the full release, https://loom.ly/QIQX9EA

08/11/2026

Precision BioSciences announced its second quarter 2026 earnings and provided a business update!

CFO, Alex Kelly, tells you what you need to know.

Read the full press release, https://loom.ly/MIhNNio

How many of the 240 million people living with chronic hepatitis B worldwide will ever receive treatment or know they ha...
07/28/2026

How many of the 240 million people living with chronic hepatitis B worldwide will ever receive treatment or know they have it?

On World Hepatitis Day, we’re reminded that hepatitis B remains a leading cause of liver cancer and liver‑related death globally, yet fewer than 5% of people living with chronic HBV are receiving treatment. Most remain undiagnosed and untreated.

At Precision BioSciences, we are striving to advance PBGENE‑HBV, our wholly owned in vivo gene editing program being evaluated in the Phase 1 ELIMINATE‑B trial, and the first and only potentially curative gene editing program to enter the clinic that is specifically designed to eliminate the root cause of chronic hepatitis B, cccDNA. Elimination of cccDNA results in HBV viral cure because cccDNA is the only source of infectious replication (HBV DNA).

On a day dedicated to hepatitis awareness, we pause to recognize the global burden of hepatitis B and the responsibility of working on approaches that aim to change what is possible for people living with this infection.

For more information, visit https://loom.ly/sBJzafI

07/20/2026

Precision BioSciences has activated a second clinical site at Washington University School of Medicine in St. Louis for the Phase 1/2 FUNCTION‑DMD trial evaluating PBGENE‑DMD in boys ages 2-7 with Duchenne muscular dystrophy.

This expansion marks another step toward assessing PBGENE‑DMD’s potential to restore near full‑length dystrophin and improve long‑term muscle function in patients with mutations between exons 45–55.

Watch our latest DMD update, https://loom.ly/t3XCnQk

At PPMD’s 2026 Annual Conference in Orlando, PBGENE‑DMD was highlighted in the “Gene Therapy: Today and Tomorrow” sessio...
07/16/2026

At PPMD’s 2026 Annual Conference in Orlando, PBGENE‑DMD was highlighted in the “Gene Therapy: Today and Tomorrow” session led by Dr. Aravindhan Veerapandiyan of Arkansas Children’s Hospital, followed by a clinician–industry panel featuring Gary Owens, Senior Director of Gene Therapy and Program Lead at Precision BioSciences.

Our team also hosted a resource booth, meeting with families and individuals with Duchenne to listen, answer questions, and share how we’re working to advance in vivo gene editing.

Interested in the latest news from PBGENE-DMD? Read, https://loom.ly/VwR_dj4

07/10/2026

In case you missed the live event, here are a few of our favorite moments from Precision BioSciences’ recent virtual investor event on Hepatitis B Virus (HBV).

Watch the full conversation to hear the Precision team and external experts discuss new biopsy and clinical data from the ongoing ELIMINATE-B trial in chronic hepatitis B.

Click here for the full replay, https://loom.ly/p8O6mSM

Advancing next‑generation neuromuscular therapies with ARCUS at the Oppenheimer CNS & Neuro‑Muscular Summit in Miami.Pre...
07/09/2026

Advancing next‑generation neuromuscular therapies with ARCUS at the Oppenheimer CNS & Neuro‑Muscular Summit in Miami.

Precision BioSciences was pleased to participate, joining leaders across neurology and neuromuscular disease to discuss next‑generation therapeutic approaches.

Chief Financial Officer Alex Kelly represented Precision BioSciences and PBGENE-DMD, the Company's development program for the treatment of Duchenne Muscular Dystrophy (DMD). Alex spoke on a panel focused on emerging treatments for genetic muscle disorders and the potential of in vivo gene editing.

At the Jefferies Global Healthcare Conference in New York, the Precision BioSciences leadership team outlined how our pr...
07/01/2026

At the Jefferies Global Healthcare Conference in New York, the Precision BioSciences leadership team outlined how our proprietary ARCUS in vivo gene editing platform is advancing programs in chronic Hepatitis B and Duchenne muscular dystrophy.

"Being added to the Russell 2000 Index broadens our visibility with institutional investors at a pivotal time for Precis...
06/30/2026

"Being added to the Russell 2000 Index broadens our visibility with institutional investors at a pivotal time for Precision BioSciences," said Alex Kelly, Chief Financial Officer of Precision BioSciences. "We are advancing two wholly owned clinical programs, PBGENE-HBV in chronic hepatitis B and PBGENE-DMD in Duchenne muscular dystrophy, with a cash runway supporting our operations through 2028."

Read the full release here, https://loom.ly/Qxmv0lE

At ASGCT 2026, Adam Mischler, PhD, DMD Research Lead at Precision BioSciences, shared new preclinical PBGENE‑DMD data su...
06/16/2026

At ASGCT 2026, Adam Mischler, PhD, DMD Research Lead at Precision BioSciences, shared new preclinical PBGENE‑DMD data supporting advancement of this in vivo gene editing candidate into the clinic.

In early‑juvenile mice, PBGENE‑DMD achieved up to 3‑times higher dystrophin protein restoration in skeletal muscle and up to 12‑times higher restoration in respiratory muscle compared with late‑juvenile mice, reinforcing the rationale for treating younger DMD patient populations.

Read the full release here, https://loom.ly/VwR_dj4

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302 E. Pettigrew Street
Durham, NC
27701

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