06/12/2026
"Writing the Biology of the People You Lead"
More phrases I love to use because it creates a long pause in the room. It is from the chapter on neuroplasticity and epigenetics in Coherent Leadership: "Every leader is, whether they realize it or not, writing the biology of the people they lead." I did not put that sentence in casually. I put it in because after years of holding executive and CEO roles myself, and the years that followed working with senior leaders across very different industries, I have come to believe it is one of the most important and least understood truths in modern organizational life.
Over the last two decades, research has made this idea impossible to dismiss. Neuroplasticity research, popularized by Norman Doidge and grounded in pioneers like Michael Merzenich, has shown that the adult human brain physically rewires itself in response to repeated experiences and environments. The patterns we are most regularly exposed to become the patterns most easily activated, and over time, the most easily lived. A team member who spends forty hours a week inside a relational environment characterized by urgency, fear, or invisibility is being neurologically trained into a default state of urgency, fear, or invisibility. A state that will follow them home and shape every relationship they walk into when they leave the office.
The work in epigenetics has gone one layer deeper. Research from Michael Meaney at McGill, Moshe Szyf, Rachel Yehuda at Mount Sinai, and a growing field of scientists working on environmental gene expression has demonstrated that our environment not only influences our behavior. It influences which of our genes get expressed and which stay silent. Chronic psychological pressure measurably upregulates stress-related gene expression. Sustained experiences of safety, recognition, and meaning support immune, regulatory, and cognitive function at the cellular level. We are not being metaphorical when we say that culture matters. We are biological organisms whose interior, at the cellular level, is being shaped by the relational environment a leader creates.
Layered on top of this, Stephen Porges's polyvagal theory has given us a precise vocabulary for what teams are actually experiencing. The human nervous system is constantly scanning for cues of safety or threat, not through cognition, but through a process Porges calls neuroception. A leader's tone of voice, facial expression, pace, and presence are not soft variables. They are biological signals that determine which branch of the autonomic nervous system a team member's body is operating from. Lead from coherence, and their nervous systems regulate toward safety, creativity, and engagement. Lead from chronic dysregulation, and their nervous systems collapse into survival mode. And survival mode does not innovate, does not collaborate, and does not love anyone deeply enough to return home as a better partner or parent.
I continue this reflection in the first comment.