Yeasen Biotechnology

01/16/2026

PAG 33 Wrap-Up｜Great Energy, Great Conversations
33 has officially wrapped up, and the energy around plant and animal genomics was impressive—discussions continued well into the evening.

One clear takeaway from the conference was the growing role of AI in bioinformatics, especially as researchers work with larger and more complex genomic datasets. At the same time, many conversations reinforced a shared view: high-quality experimental data is still the foundation of meaningful analysis.

We were happy to connect with researchers and partners from around the world, exchange ideas, and learn more about current challenges and emerging trends in genomics and NGS.

Thanks to everyone who took the time to chat with us—we look forward to staying connected beyond 33.

01/13/2026

has been buzzing all day — and even by 8 or 9 pm, the halls were still full of people.

The strong engagement around topics such as complex genome assembly, pan-genome analysis, and functional validation reflects the vitality of the plant and animal genomics community.

AI in bioinformatics kept coming up again and again in conversations, and it's exciting to see how fast things are moving in plant and animal genomics.

Really happy to be part of and to connect with so many colleagues and new friends through great discussions.

If you're at the conference, feel free to stop by and chat with me — I'd love to hear your thoughts!

11/21/2025

🐴 Unexpected visitors at UC Riverside!

While out on a customer visit, our sales colleague ran into a group of wild burros wandering across campus — only in California!

To everyone working hard in the lab:
✨ When research gets exhausting, don’t forget to pause and enjoy the little joys around you.

Even a busy day can hold a small surprise.

11/20/2025

🔥 Top labs are racing for T4 RNA Ligase 2!

Meet Yeasen T4 RNA Ligase 2 — your “molecular glue” for tricky dsRNA and RNA→DNA ligations, matching imported brands! 💯

🌟 Why it stands out:
ꔷ Expert dsRNA ligation — joins RNA gaps & RNA 3’-OH to DNA 5’-phosphate
ꔷ Ultra-pure & high activity — multi-step purified, no contaminating enzymes
ꔷ Cost-effective — top quality without the high price

🔬 How it works:
~37 kDa, with conserved domains forming a precise nucleotide-binding pocket for efficient catalysis.

💡 RNA ligation made easy — product link in the comments!
👉 Facing ligation challenges? Comment below!

11/18/2025

🎯 Think your miRNA really hits its target? Let the data speak!

Dual-luciferase reporter assays provide a reliable readout of miRNA–target interactions:
Construct WT/MUT reporters with your target 3'UTR.
Transfect cells with miRNA mimics or negative controls.
Measure Firefly & Renilla luciferase, calculate relative activity.

✅ Key insight: If the WT + target miRNA mimic shows reduced relative luciferase activity, while the MUT controls remain unchanged → your miRNA binds the 3'UTR directly.

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💬 Curious how your favorite miRNA performs? Share your results or questions below!

11/14/2025

✨ Step into AMP 2025 with us ✨

From the first moment at the convention center → the busy halls → the big names → to the good vibes at Booth 131 — here’s a little behind-the-scenes from our day at AMP.

So many brilliant researchers, clinicians, and innovators all in one place.
Such an energy. Such a community. 💙

We’re grateful to be part of it — and yes,
our booth is open, come say hi anytime!

More highlights coming soon 🎥✨

11/13/2025

🚀 Case 6: Primary Skin Fibroblast Transfection
Even large plasmids (6.1 kb!) can achieve over 90% efficiency 👏

Thanks to Hieff Trans™ Booster, which consistently outperforms other brands in side-by-side tests 💪

💡 Pro Tips:
• Aim for 70–80% confluence — timing is everything.
• Skip antibiotics during complex formation ❌
• Always dilute DNA & reagent in Opti-MEM, not serum medium ⚗

Stable. Bright. Efficient.
Booster delivers every time.

11/12/2025

Still juggling three transfection kits?
You don’t have to tell me.
One Booster does it all — DNA, mRNA, siRNA.

Polymer-based design ensures low toxicity and high efficiency, even in sensitive or hard-to-transfect cells.

No more juggling protocols, wasting time, or compromising cell viability — Booster makes every transfection simple and reliable.

Whether it’s primary cells, large fragments, or multiple nucleic acids, one reagent handles it all.

💡 Experience the difference yourself — apply for a Booster test kit (40801) in the comments below!

11/11/2025

Case 5: High-Efficiency Transfection in AC16 Human Cardiomyocytes 💚

AC16 cells finally glow with confidence!

🏆 48 h Fluorescence Comparison:
Transfection efficiency skyrocketed from

11/10/2025

🧬 Transfect Primary Macrophages with Ease
Hard-to-transfect? Not anymore.

Hieff Trans™ Booster (Cat #40801) delivers >90% efficiency and low cytotoxicity in primary BMDMs and 200+ cell types.

Try it free — check out the full protocol & sample request here:
Protocol for Transfection of Primary Bone Marrow-Derived Macrophages (BMDMs)：https://hubs.la/Q03Sltxc0

1. Experimental Materials BMDM Cells Target plasmid DNA (Concentration ≥ 1000 ng/μL) Hieff TransTM Booster DNA&RNA Transfection Reagent (Cat #40801)（Know more and get Free Sample） Opti-MEM Reduced Serum Medium Compatible tissue culture plates and related lab consumables (using a 24-well pl...

11/07/2025

🧬 Yeasen at AMP 2025 | Booth #131
Yeasen is proud to participate in the Association for Molecular Pathology (AMP) 2025 Annual Meeting & Expo, taking place November 11–15 in Boston, MA.

At Booth #131, we will showcase our Hieff NGS™ library preparation portfolio — engineered to deliver high efficiency, accuracy, and reproducibility for both RNA and DNA sequencing applications.
Explore our latest innovations, including the EvoMax RNA/DNA Library Prep Kits and OnePot Flash DNA Library Prep Kit, designed to streamline molecular diagnostics and accelerate precision medicine.
We look forward to connecting with leaders and innovators shaping the future of molecular pathology.

✨ Full details and links can be found in the comments below.