Kepley BioSystems

Kepley BioSystems Kepley BioSystems is a North Carolina-based life sciences start-up founded in 2013 with a mission to emerge disruptive innovations to achieve global solutions.

Kepley BioSystems Inc, a North Carolina start-up, has developed ocean restorative technology to help stem the continued depletion of wild fish, while at the same time, addressing a multi-billion dollar market. We have developed a (patent pending #14/659,710 and /US2015/2086) synthetic crustacean bait formulated to replace the use of wild fish stocks as the primary bait in
commercial lobster an

d crab traps. Crustacean fishing is a $66 billion global market that consumes
over 18 million metric tons of bait fish for these traps at a cost of an estimated $20 billion per year. This new product epitomizes the emerging trend of “Blue Ocean” innovations by merging
ecology and enterprise within the currently $500 billion fishing industry. Companies like Kepley
BioSystems are working toward significant, sustainable contributions to oceanic species
preservation; in addition, these environmentally friendly enterprises are meeting the nutritional and
food safety needs of the global seafood market and helping ensure political stability worldwide.

This is it! The last hour of voting is here. Vote for us in the Finals for the Triad's most innovative small business! I...
03/15/2022

This is it! The last hour of voting is here. Vote for us in the Finals for the Triad's most innovative small business! It takes less than a minute, so please click the link below and vote for Kepley BioSystems:

https://www.bizjournals.com/triad/pulse/survey/triad-inno-madness-the-final-matchup/22049866

Continuing from yesterday's post, the sheer danger presented by sepsis is staggering. Doctors and nursing staff are keenly adept at noticing the onset of sepsis, but once symptoms present, it becomes a race against the clock to get the infection under control and save the patient's life.

Our innovative blood infection surveillance tool is designed to work within a normal hospital workflow and could be added to normal daily blood panels. With results in 1-3 hours (compared to a blood culture test, which can take up to 2-7 days), clinicians can be armed with the information they need to fight sepsis before symptoms present, while it can be cured most easily.

03/14/2022

Vote for us in the Finals for the Triad's most innovative small business! It takes less than a minute and ends Tuesday at noon, so please click the link below and vote for Kepley BioSystems:

https://www.bizjournals.com/triad/pulse/survey/triad-inno-madness-the-final-matchup/22049866

For the last couple of weeks, we've discussed our overarching strategy to conserve horseshoe crabs, provide a critical assay needed for clinical medicine, and our ultimate goal of creating a tool that can detect a blood infection before sepsis can set in.

Today, we'll talk about why sepsis is such a danger to patients around the world. Sepsis is the body's reaction to an infection in the blood system, and that response can be life-threatening, leading to organ shutdown, tissue damage, and ultimately death. If the infection is found and treated quickly, the spiral of sepsis can be halted with the correct antibiotics. However, for each hour the infection goes untreated, a patient's odds of survival plummet by 8% per hour.

Sepsis is the number one cost for US hospitalizations, adding an additional $62 billion expenses annually. More staggering though is that, on average, sepsis claims a life somewhere on the planet every 2.8 seconds.

03/13/2022

Vote for us in the Finals for the Triad's most innovative small business! It takes less than a minute, so please click the link below and vote for Kepley BioSystems:

https://www.bizjournals.com/triad/pulse/survey/triad-inno-madness-the-final-matchup/22049866

In the last post, we showed you our proprietary horseshoe crab feed and how it is designed to be nutritious and easy for the crabs to eat. The horseshoe crab has an interesting anatomical trait: its mouth is in-between its walking legs. Surrounded by toothbrush-like bristles, the crab's mouth "chews" as the animal walks along the ocean floor.

For illustrative purposes, we've flipped this one upside down so that you can see how it eats its food. Please forgive the wonky camerawork, as she only barely put up with such indignity.

Vote for us in the Finals for the Triad's most innovative small business! It takes less than a minute, so please click t...
03/11/2022

Vote for us in the Finals for the Triad's most innovative small business! It takes less than a minute, so please click the link below and vote for Kepley BioSystems:

https://www.bizjournals.com/triad/pulse/survey/triad-inno-madness-the-final-matchup/22049866

Animals in captivity tend to suffer from poor nutrition due to the homogeneous natures of their daily diets and traditional aquaculture manufactured feeds focus on getting a fish to market as quickly as possible.

Our team knew that approach would not work for our overall plan, so we invented our own sustainable and nutritious feed formulation. Our proprietary feed ensures our crabs' diet exceeds nutritional needs for happy and healthy horseshoe crabs.

Thanks to everyone's shares and votes, we made it to the finals in the Triad Business Journal Inno Madness competition! ...
03/10/2022

Thanks to everyone's shares and votes, we made it to the finals in the Triad Business Journal Inno Madness competition! One more round to go! It takes less than a minute, so please click the link below and vote for Kepley BioSystems:

https://www.bizjournals.com/triad/pulse/survey/triad-inno-madness-the-final-matchup/22049866

The LAL assay required for our sepsis surveillance tool comes from the blood of the horseshoe crab, so we set out to find the most sustainable and ethically responsible way to husband the animals. We compared both an outdoor "ranch-style" pen in a natural body of water and an indoor aquaculture system with pristine water. In the end, the indoor system proved to maintain the healthiest crabs and allowed us to produce LAL with far less variation than that taken from wild stocks. We currently operate that indoor system here in the NC Triad.

03/09/2022

WE'RE IN THE FINALS! Thanks to everyone's shares and votes, we made it to the finals in the Triad Business Journal Inno Madness competition! One more round to go! It takes less than a minute and you can vote by clicking the link below:

https://www.bizjournals.com/triad/pulse/survey/triad-inno-madness-the-final-matchup/22049866

This week we'll discuss our innovations in horseshoe crab aquaculture and show off a few more of these amazing creatures! Please let us know any questions you may have, and we'll answer those too!

03/08/2022

We're in the last hour of voting, and the score is super close! Vote for us for the Triad Business Journal Triad Inno Madness contest for most innovative small business! It takes less than a minute, so please click the link below and vote for Kepley BioSystems in Matchup #2.

https://www.bizjournals.com/triad/pulse/survey/triad-inno-madness-round-3/22046341

We're at the buzzer, but our team cannot thank you enough for all the sharing and voting. It has been an amazing response! Today, I'll share a quiet moment of a few of our crabs just hanging around in the lab. Enjoy the peaceful moment of crab tranquility, and then let's finish strong! Go, go, go, go, go!

Sincerely, thanks from the entire Kepley team.

Today is the last full day to vote this round! Vote for us for the Triad Business Journal Triad Inno Madness contest for...
03/07/2022

Today is the last full day to vote this round! Vote for us for the Triad Business Journal Triad Inno Madness contest for most innovative small business! It takes less than a minute, so please click the link below and vote for Kepley BioSystems in Matchup #2.

https://www.bizjournals.com/triad/pulse/survey/triad-inno-madness-round-3/22046341

Yesterday, we discussed the Limulus Amebocyte Lysate (LAL) and how it works. The team at Kepley BioSystems, with funding from the National Science Foundation, developed a way to use LAL in clinical medicine using whole human blood for the first time, which opens exciting new possibilities.

Globally, one life is lost to sepsis every 2.8 seconds. Sepsis can be treated easily if the infection is discovered early, but becomes deadlier by the hour. With successful feasibility trials finished, our innovation has the potential to be an affordable rapid blood infection surveillance tool, able to help doctors catch and treat sepsis before it can cause irreversible organ and tissue damage. We are now working to bring this tool to the next stages, and ultimately help doctors get the information they need to make life-saving decisions more quickly.

We're in a dead heat right now! Vote for us in the semifinals for the Triad Business Journal Triad Inno Madness contest ...
03/07/2022

We're in a dead heat right now! Vote for us in the semifinals for the Triad Business Journal Triad Inno Madness contest for most innovative small business! It takes less than a minute, so please click the link below and vote for Kepley BioSystems in Matchup #2.

https://www.bizjournals.com/triad/pulse/survey/triad-inno-madness-round-3/22046341

Yesterday, we discussed the horseshoe crab's incredible amebocyte cell. This cell acts as the basis of the horseshoe crab's immune system by finding pathogens and harmful bacteria, surround the infection, and creating a firm gel-like clot. This clot neutralizes the pathogen and protects the crab. Currently, we use this cell to create the Limulus Amebocyte Lysate (LAL) assay and use it to test any thing that comes into contact with the human bloodstream. Basically, any shot, implant, or medical device that goes into a human must be tested with LAL to ensure that it is not contaminated and so that you are kept safe from infection.

Tomorrow, we'll tell you how Kepley BioSystems innovations take this established technology further and, for the first time, can help protect patients from sepsis. Don't forget to vote and share!

We’re catching up! Vote for us in the semifinals for the Triad Business Journal Triad Inno Madness contest for most inno...
03/05/2022

We’re catching up! Vote for us in the semifinals for the Triad Business Journal Triad Inno Madness contest for most innovative small business! It takes less than a minute to vote, so please click the link below and vote for Kepley BioSystems in Matchup #2.

https://www.bizjournals.com/triad/pulse/survey/triad-inno-madness-round-3/22046341

Here’s today’s Horseshoe Crab fact. The blood of horseshoe crabs is a very pleasant blue color due to being copper-based (instead of the iron that makes our blood red). This blue blood also contains a special cell called an “amebocyte” that acts as the basis of their robust immune system by seeking out and neutralizing pathogens and harmful bacteria. Tomorrow, we’ll discuss how it works and how it keeps us humans safe too! Don’t forget to share and vote!

Thanks to your votes, we're in the semifinals for the Triad Business Journal Triad Inno Madness contest for most innovat...
03/04/2022

Thanks to your votes, we're in the semifinals for the Triad Business Journal Triad Inno Madness contest for most innovative small business! But we need your help (it takes less than a minute to vote — once per round). Please click the link below and vote for Kepley BioSystems in Matchup #2.

https://www.bizjournals.com/triad/pulse/survey/triad-inno-madness-round-3/22046341

Meanwhile, we'll share a fact each day about how horseshoe crabs lead our innovations. Ancient fossils of horseshoe crabs have been found, indicating lineage as far as 300-450 million years old. They have survived 5 mass extinctions that annihilated most other life on earth. This can be partly attributed to their elegant immune system. In future updates, we'll discuss their unique blood, how it is important to human health, and how Kepley BioSystems is working with this amazing species. Stay tuned, and please keep voting!

We made it to the second round of Triad Inno Maddness! One of our horseshoe crab buddies wanted to thank you for all you...
02/28/2022

We made it to the second round of Triad Inno Maddness! One of our horseshoe crab buddies wanted to thank you for all your votes.

But its not over yet, the current round is neck and neck. We really need your vote to be crowned the most Innovative Company in the Triad Inno Madness brackets. Please click the link below and vote for Kepley BioSystems in Matchup #4.

https://www.bizjournals.com/triad/pulse/survey/triad-inno-madness-round-2/22042741

Address

2901 East Gate City Boulevard Suite 2400
Greensboro, NC
27401

Opening Hours

Monday 8am - 5pm
Tuesday 8am - 5pm
Wednesday 8am - 5pm
Thursday 8am - 5pm
Friday 8am - 5pm

Telephone

+13362175163

Website

Alerts

Be the first to know and let us send you an email when Kepley BioSystems posts news and promotions. Your email address will not be used for any other purpose, and you can unsubscribe at any time.

Shortcuts

Share