02/25/2026
When using automated or MLA+ pipettes, you should NOT have to force the tips on. If you do, they are the incorrect tips. You can always check to see if they fit correctly by pulling up some DH20 and hold upright. If it leaks, it isn't a correct fit.
When I recently attempted to use an automated pipette, one that's used for molecular, I was told by the tech that I needed to force the tip on. Even then, it still dripped. So I would question how accurate this is when using for testing, etc.
Also of note, volumetric pipettes should be used to make up calibrator and controls. Not serological or automated. Volumetric pipettes have a bulb in the middle which helps to remove any bubbles when dispensing. Serological is not as accurate. Here's a picture of volumetric piepttes.