Integrated Micro-Chromatography Systems

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Integrated Micro-Chromatography Systems A leader in recombinant enzymes and automated micro-chromatography technologies. The company has two product lines: IMCSzyme® and IMCStips®.

We understand the importance of accuracy, which is why we are committed to delivering products that consistently provide fast, reliable results. Company History
Integrated Micro-Chromatography Systems, Inc (IMCS) was founded in January 2013 by three scientists from the University of South Carolina. IMCS designs, develops, manufactures, and distributes next-generation recombinant proteins and chromatography consumables to clinical and forensic toxicology laboratories, academic research facilities, US government agencies, and health science companies worldwide. The industry-disrupting IMCSzyme is a genetically modified enzyme primarily used by clinical, forensic, and pain care laboratories for the drug screening and analysis of urine and other biological samples. IMCStips are advanced micro-chromatography products centered around patented dispersive solid-phase extraction (dSPE) technology containing loosely packed resin for faster biochemical purification processes. IMCStips are utilized by academic laboratories and health science companies for purifying new proteins, antibodies and enzymes, as part of drug target discovery and validation, drug development, drug screening, and drug manufacturing. Recently, IMCS was awarded NIH SBIR and STTR funds to manufacture various glycosyltransferases to leverage the company’s advanced manufacturing and research capabilities to expand the synthesis of glycosphingolipids and sialoglycans. This expansion provides IMCS with new product lines and delivers critically needed biological reagents that were not previously available to the scientific community.

It is time for the international leg of our fall   events! 👀 IMCS is heading to   2026 in just one month. We’re looking ...
10/13/2026

It is time for the international leg of our fall events! 👀

IMCS is heading to 2026 in just one month. We’re looking forward to connecting with researchers and sharing how can help streamline your workflows.

📅 Save the date and come say hello!

👀 They may look familiar...If you've been following us for a while, you've probably already met our   and   mascots. How...
10/08/2026

👀 They may look familiar...

If you've been following us for a while, you've probably already met our and mascots. However, a proper introduction is WELL overdue! For the first time, we would like you to officially meet Enzo and Tipothy! 🧪💙

Why is 5 µL enough? 👀The data speaks for itself. From speed and substrate coverage to recovery and inhibitor resistance,...
09/29/2026

Why is 5 µL enough? 👀

The data speaks for itself. From speed and substrate coverage to recovery and inhibitor resistance, there’s a lot behind those 5 µL.

Read below to see the data behind 👇

If you stopped by our booth at  , you may have heard us talking about just how far 5 µL can go.🤔  requires just 5 µL of ...
09/24/2026

If you stopped by our booth at , you may have heard us talking about just how far 5 µL can go.🤔

requires just 5 µL of enzyme per 50 µL of urine to achieve >90% hydrolysis in 15 minutes or less. For comparison, a recent study showed a premixed competing enzyme required up to 100 µL and still failed to hydrolyze. 😧

Click here to get a free sample to see the results of your own panel using just 5 µL 👉 https://bit.ly/4yVBDrb

Day✌️of   is starting off strong! Dr. Andrew Lee is presenting his poster TODAY. He will discuss how “enzyme blind spots...
09/22/2026

Day✌️of is starting off strong! Dr. Andrew Lee is presenting his poster TODAY. He will discuss how “enzyme blind spots” present a risk of incomplete hydrolysis and false negatives.

➡️Poster #168
➡️Title: Identifying Glucuronide Substrate Biases in β-glucuronidases for Toxicology Applications
➡️Presenting at 12:00 PM - 1:30 PM

If you are unable to make it to the show, download a version of the poster now 👉 https://bit.ly/4rvVw5O

SOFT-TIAFT 2026 is finally here! IMCS is in Chicago at booth 520. Stop by our booth to "tox" to us about:1️⃣ Getting >90...
09/22/2026

SOFT-TIAFT 2026 is finally here! IMCS is in Chicago at booth 520. Stop by our booth to "tox" to us about:

1️⃣ Getting >90% hydrolysis with ONLY 5µL of
2️⃣ Our latest data
3️⃣ How to save $$$ and time
4️⃣ Your hydrolysis questions
5️⃣ How to get your hands on our swag

See you soon! 👋

The   Fall Events start in ONE MONTH! Anusha Chaparala and William Murphy will be representing IMCS in...➡️The Bay Area➡...
09/17/2026

The Fall Events start in ONE MONTH! Anusha Chaparala and William Murphy will be representing IMCS in...

➡️The Bay Area
➡️New England
➡️Seattle

If you're attending any of these shows, please stop by and say hi.👋 We hope to see you there!

The joint   meeting is only TWO weeks away! Be the first to know about our poster presentation📊:➡️Poster  #168➡️Identify...
09/08/2026

The joint meeting is only TWO weeks away! Be the first to know about our poster presentation📊:

➡️Poster #168
➡️Identifying Glucuronide Substrate Biases in β-glucuronidases for Toxicology Applications
➡️Presented by IMCS CEO, Dr. L. Andrew Lee

We can't wait to high-𝙛𝙞𝙫𝙚 you at our booth ( #520)! See you there🖐️

08/20/2026

Only 1 month until we head to Chicago for the Joint Meeting! If you are attending as well, we’ve got 5 reasons you’ll want to make Booth 520 one of your stops! 👀

Check back for more details on our poster presentation. See you in Chicago! 👋

Address

110 Centrum Drive
Irmo, SC
29063

Opening Hours

Monday 9am - 5pm
Tuesday 9am - 5pm
Wednesday 9am - 5pm
Thursday 9am - 5pm
Friday 9am - 5pm
Sunday 9am - 5pm

Telephone

+18885602073

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