Kimera Labs

04/08/2020

microRNA contained within MSC exosomes reduces expression of inflammatory proteins involved in the cytokine storm that causes lung damage in COVID-19.

🧬miR-146a-5p reduces the levels of inflammatory mediators (eg. IL-6 & TNF-α) and increases the level of anti-inflammatory mediators (ie. IL-10). This microRNA also promotes polarization of macrophages, immune cells responsible for removal of cellular debris, to a more regulatory type (ie. M1 → M2) that reduces the level of inflammatory mediators and increases clearance of pathogens, microbes and damaged cells.

🧬miR-223 reduces the levels of the most important inflammatory mediators (eg. TNF-α, IL-1β, IL-6, NF-κB) involved in the inflammatory response that causes cytokine storm.

🧬Reduction in the levels of inflammatory mediators could help to arrest the progressive damage to the lungs that occurs in more severe cases of COVID-19.

02/29/2020

Adam Koster and Sara Watson are representing Kimera at A4M’s Bio-Identical Hormone Replacement Symposium this weekend. Stop by our booth to learn how you can incorporate Kimera Exosomes into your practice!

02/27/2020

🧬XoGlo®🧬
Purified Mesenchymal Stem Cell (MSC)-Derived Exosomes

XoGlo® is a sterile suspension of purified mesenchymal stem cell (MSC)-derived exosomes. This cosmetic product contains a multitude of growth factors, which are involved in skin repair, beautification and regeneration.

🧬Amnio2X®🧬
Amniotic Fluid Exosomes

Amnio2X® is a sterile-filtered amniotic fluid-derived exosome product. Amniotic fluid contains billions of exosomes. Twice the growth factors, twice the potential healing of un-processed amniotic fluid.

02/21/2020

Dr. Jason Sanders and Brett Gibbs are representing Kimera Labs this weekend at the Miami Cosmetic Surgery Conference at the Miami Convention Center. If you are attending, stop by booth 119 in the exhibit hall!
Do not miss Dr. Gregory Chernoff’s presentation, The Utilization of Exosomes in Aesthetics and Reconstructive Surgery tomorrow at 11am in room 240-241!

02/12/2020

Kimera Labs offers a monthly seminar where leading exosome scientists, physicians and surgeons present the latest progress in exosome-related scientific development and clinical research.
These ‘XO Expos’ are offered at the Kimera Labs campus, a 27,000 sqft exosome production and research facility, present visitors with an opportunity to learn about the latest scientific and clinical developments related to exosomes, and a chance to see, first-hand, how MSC exosomes are produced and evaluated with the most sophisticated instrumentation available.

Do not miss our next XO Expo on Saturday, February 22nd at 8am. To register, visit exosomes.com.

02/10/2020

Analysis of a sample of Kimera exosomes: dSTORM super resolution fluorescence microscopy detects labeled antibodies for CD 63 & 81 & visualizes individual mesenchymal stem cell exosomes.

02/04/2020

NATURAL CELLULAR COMMUNICATION
🧬Exosomes are nano-scale extracellular vesicles, extremely small membrane-enclosed vessels, one thousandth the size of a cell, that contain the biologic message of their parent cells.
🧬They are produced by virtually every cell type as a means of intercellular communication.
🧬Exosomes contain proteins such as growth factors, enzymes, receptors, transcription factors and matrix proteins that govern cell structure, function and signaling.
🧬They also contain messenger RNA (mRNA), the blueprint for protein production, and micro RNA (miRNA), an important intracellular signaling mediator.

01/31/2020

Dr. Spiel, Dr. Sanders, and our CEO Dr. Ross are always eager to share their exosome expertise.

As the leader in the field of MSC exosome research and development, Kimera Labs is dedicated to the education of physicians and scientists alike to accelerate development of exosome-based diagnostic and therapeutic modalities.

01/28/2020

01/24/2020

STORM super-resolution fluorescence microscopy of Kimera exosomes on 1/23/20 shows single-molecule fluorescence of individual CD 63 & 81 proteins on the surface of a 120 nm exosome, indicating MSC origin.

01/13/2020

Dr. Jian Jun Shi conducting flow cytometry studies for exosome research & development at our laboratory in Miramar, FL.

🧑🏻‍🔬Dr. Shi is a post-doctoral cell biologist, who has extensive experience with gene therapy and cell culture and has served as director of research and development at Kimera Labs, Inc since June 2018.
🧑🏻‍🔬He brings over 10 years of industrial and academic research experience with publications in molecular biology, cell biology and immunology.
🧑🏻‍🔬He is proficient in cell culture techniques of mammalian cells, primary cells, and pluripotent stem cells, including differentiation assays and viral transduction.
🧑🏻‍🔬He is also well versed in genetic recombination, RNA-Sequencing, tissue histology, multicolor flow cytometry, gene expression assays, and data analysis.

01/09/2020

Visit exosomes.com to register for one of our upcoming events in Miami, FL.

Dates:
JAN 18 & 19
FEB 22 & 23
MAR 14 & 15
APR 18 & 19