BridgeBio

BridgeBio We move at the speed of patient need.

The date is locked in for LGMD2I/R9. The FDA has accepted our NDA for BBP-418 for LGMD2I/R9 and set a PDUFA target actio...
05/27/2026

The date is locked in for LGMD2I/R9.

The FDA has accepted our NDA for BBP-418 for LGMD2I/R9 and set a PDUFA target action date of November 27, 2026, the date by which the FDA will complete its review.

LGMD2I/R9 is a progressive, life-shortening disease with no approved treatments. If BBP-418 is approved, it would be the first for LGMD2I/R9, and potentially for any form of .

For a community that has lived with no approved treatment options, timing is everything. We're racing toward potential approval and preparing for launch so that those with LGMD2I/R9 can be reached as quickly and safely as possible.

When we say we're committed to the communities we serve, we mean it.We were proud to be part of the 94th Midwestern Regi...
05/22/2026

When we say we're committed to the communities we serve, we mean it.

We were proud to be part of the 94th Midwestern Regional Convention of Phi Alpha Fraternity, where we raised awareness about ATTR-CM.

ATTR-CM is a progressive heart condition with two forms: wild-type ATTR-CM, an age-related form that can affect anyone, and hereditary ATTR-CM (V122I variant), a genetic form carried by approximately 3–4% of people of African descent. Both types are significantly underdiagnosed in Black communities.

Events like this one are how we close that gap by providing education around the condition. Not by waiting. By showing up.

: “It is important to really be able to come together for a common cause – to figure out what their family medical histo...
05/21/2026

: “It is important to really be able to come together for a common cause – to figure out what their family medical history is and help future generations.”

For some families, genetic testing can help connect the dots across generations.

is a type of genetic hypoparathyroidism that may cause symptoms like tingling around the mouth or fingertips, muscle fatigue, and brain fog. Over time, it may also lead to more serious health complications.

But many people with low calcium may not realize these symptoms could be linked to a genetic condition.

At a recent gathering hosted by the patient advocacy group, HypoPARAthyroidism Association, Inc. (HPA) in Oklahoma City, families came together to learn more about their shared family history of low calcium levels and participate in genetic testing with a simple cheek swab.

For many families, getting tested isn’t just about answers today – it’s about helping future generations understand their health.

Watch the video to hear their stories and learn why genetic testing matters: https://bit.ly/4bM7AcB

05/18/2026

🚀 A major step forward for the limb-girdle muscular dystrophy (LGMD) community is here! The Muscular Dystrophy Association and BridgeBio are partnering on a $100,000 investment to strengthen multidisciplinary care for people living with LGMD at leading MDA Care Centers at Stanford Health Care and the University of Minnesota.

These innovative projects will help expand access to care, strengthen coordination across specialties, and support hybrid care models that meet patients where they are. 🩺✨

🔗Read the full story: https://www.mda.org/press-releases/mda-announces-100000-investment-to-advance-lgmd-care-at-leading-mda-care-centers-with-bridgebio

05/14/2026

/PRNewswire/ -- Every year, countless women are told their breathlessness is stress, their fatigue is menopause, and their heart symptoms are "something else."...

We have two major updates to share on encaleret, our oral therapy in development for individuals with  . ✅ This week at ...
05/12/2026

We have two major updates to share on encaleret, our oral therapy in development for individuals with .

✅ This week at the 2026 European Congress of Endocrinology ( ), we presented primary results from our Phase 3 CALIBRATE.

✅ We've also submitted a New Drug Application (NDA) to the FDA for encaleret in ADH1. If approved, this would be the first therapy specifically designed for this disease.

For the patients and families living with ADH1, we know the stakes and we're committed to working with urgency to get this medicine across the finish line. Stay tuned for updates as our review with the FDA progresses.

Happy Mother's Day to the moms who hold it all together even when the road is uncertain. To every mother who has fought ...
05/10/2026

Happy Mother's Day to the moms who hold it all together even when the road is uncertain.

To every mother who has fought for answers, found community in unexpected places, and chosen hope even on the hardest days: today is for you.

Watch the Mothers of Resilience video developed by the Curelgmd2i Foundation and supported by BridgeBio, and meet some of the remarkable women who exemplify this: https://www.youtube.com/watch?v=atbvFVfvtKs&feature=youtu.be

We recently attended the Canavan Foundation Theater Benefit, hosted by Orren Alperstein.The Canavan Foundation exists to...
05/09/2026

We recently attended the Canavan Foundation Theater Benefit, hosted by Orren Alperstein.

The Canavan Foundation exists to support families living with Canavan disease: funding research, advancing carrier screening, and expanding access to prenatal testing. That mission is one we stand behind completely.

Thank you to the Canavan Foundation for the invitation & for the work you do every day.

04/30/2026

When someone you love is waiting for a medicine that doesn't exist yet, every day matters.

That's what drives us.

We build medicines differently and we believe the people living with rare genetic conditions deserve more than a waiting list.

There are more than 10,000 rare diseases. Millions of people living with conditions that don't have an approved treatment. For thousands of those diseases, we already understand the genetic cause. That means we have a real starting point. And we refuse to waste the opportunity.

Every extra minute on the wrong path is time patients don't get back. We are Impatient for Patients.

Watch our story here: https://bit.ly/4w5vo3u

Have you heard of ATTR-CM? For many people, symptoms like shortness of breath, fatigue, leg swelling, and carpal tunnel ...
04/28/2026

Have you heard of ATTR-CM?

For many people, symptoms like shortness of breath, fatigue, leg swelling, and carpal tunnel go unrecognized for years. They're often chalked up to aging or more common forms of heart failure. But they can point to something else.

Today, in partnership with award-winning actor Freeman and “H” White, a longtime basketball apparel marketing executive, cultural connector, and heart health advocate, we launched Don't Pass On Your Heart Health to help change that. Because the earlier ATTR-CM is recognized, the more that treatment can do.

We've built free resources for anyone who wants to learn more or prepare for a conversation with their doctor.

Learn more: https://bit.ly/4tjdXdf

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