Dawson Cell Biophysics Lab

10/16/2025

Explore our groundbreaking cancer research on our website and discover how innovative biophysical analysis can transform cancer treatment. Join us in the fight against cancer by staying informed and engaged with our latest findings.

10/26/2024

Love the new I-BEAM photos of my lab!

06/10/2024

Congratulations to Andrew Howes for his first author publication! Please check out this new article from my lab.

Senescent cell accumulation in the pulmonary niche is associated with heightened susceptibility to age-related disease, tissue alterations, and ultimately a dec

03/20/2024

Congratulations to Deepraj Ghosh for his ACS Pilot Award!!

12/13/2023

https://mdanderson.cloud-cme.com/course/courseoverview?P=0&EID=32342

MDA, 1st International Conference on Polyploid Giant Cancer Cells: Biology and Clinical Applications, 2/16/2024 7:00:00 AM - 2/17/2024 5:00:00 PM, This international conference aims to unite cancer scientists, pathologists, clinicians, and experts specialized in Diagnost...

12/13/2023

Recent paper alert! Metronomic and single high-dose paclitaxel treatments produce distinct heterogenous chemoresistant cancer cell populations.

More than 75% of epithelial ovarian cancer (EOC) patients experience disease recurrence after initial treatment, highlighting our incomplete understanding of how chemoresistant populations evolve over the course of EOC progression post chemotherapy treatment. Here, we show how two paclitaxel (PTX) t...

12/13/2023

Recent paper alert! Spatial Heterogeneity in Cytoskeletal Mechanics Response to TGF-β1 and Hypoxia Mediates Partial Epithelial-to-Mesenchymal Transition in Epithelial Ovarian Cancer Cells

Metastatic progression of epithelial ovarian cancer (EOC) involves the partial epithelial-to-mesenchymal transition (EMT) of cancer cells in the primary tumor and dissemination into peritoneal fluid. In part to the high degree of heterogeneity in EOC cells, the identification of EMT in highly epithe...

06/14/2023

Proudly presenting dawsoncellbiophysics.com. Check it out and let me know what you think!

Studying outlier populations of invasive cancer cells and mechanisms they use to evade treatment

05/31/2023

New article from my lab: "Differential Response to Mechanical Cues in Uterine Fibroid Versus Paired Myometrial Cells" has been published online in Reproductive Sciences.

This work, which was led in my lab by Dr. Ghosh, was done in collaboration with Dr. Schutte from the University of Cincinnati.

Uterine leiomyomas, or fibroids, are common, benign tumors for which hysterectomy is the only definitive treatment. The extracellular matrix of fibroids is disorganized and stiffer than the surrounding myometrial tissue. To understand how stiffness affects fibroid cells, patient-matched fibroid and....