INDIGO Biosciences, Inc

INDIGO Biosciences, Inc Bring the power of INDIGO to your lab with convenient lab-in-a box Nuclear Receptor Assay Kits. Or put our experts to the test with Contract Screening.

INDIGO Biosciences, Inc. was founded in 2005 in State College, PA. It remains a privately held biosciences company offering products and services focused on nuclear receptors, which comprise a major class of therapeutic drug targets. The Company's two founders, Dr. Jack Vanden Heuvel and Dr. Blake Peterson, leveraged their collective expertise's in nuclear receptor biology, toxicology, medicinal c

hemistry and molecular biology to establish the core platform technology of The Company. INDIGO Biosciences' original focus was that of a traditional contract research organization, namely, to provide custom services for the screening of small molecule compounds against functional human and non-human nuclear receptors. Over the years, The Company has demonstrated success in providing quality screening services to clients within the pharmaceutical, biotechnology, food, agriculture and nutriceutical industries, government research agencies, as well as to academic researchers.

The INDIGO team recently came together for a potluck to celebrate our Q2 workiversaries!We’re grateful for the dedicatio...
06/15/2026

The INDIGO team recently came together for a potluck to celebrate our Q2 workiversaries!

We’re grateful for the dedication, teamwork, and energy each team member brings to INDIGO year after year. 🧪🎉🍰

See How Cross-Species Receptor Assays Supported Published ResearchCross-species comparisons can be critical when researc...
06/12/2026

See How Cross-Species Receptor Assays Supported Published Research
Cross-species comparisons can be critical when researchers need to understand whether biological activity observed in one model is likely to translate across systems.

In a Nature publication, "Bile salt hydrolase catalyses formation of amine-conjugated bile acids," researchers used INDIGO Biosciences reporter assay kits to evaluate how bacterially conjugated bile acids activated ligand-responsive transcription factors across human and mouse receptor systems. The study included receptor assays relevant to translational biology, helping demonstrate how comparative receptor data can support interpretation of biologically complex findings.

Read the paper here https://hubs.la/Q04kTm_R0

🚨B1R & B2R Assays Now Available!🚨We're excited to announce the latest addition to our assay catalog: the Human Bradykini...
06/11/2026

🚨B1R & B2R Assays Now Available!🚨
We're excited to announce the latest addition to our assay catalog: the Human Bradykinin B1R & B2R Receptors (B1R & B2R)!

This new assay equips researchers with a toolkit to characterize Bradykinin pathways, accelerating the development of therapeutics for metabolic, endocrine, and neurodegenerative disorders.

Learn about these assays and more on our website: https://hubs.la/Q04kT5Dd0

Rediscover INDIGO's Melanocortin Receptor Assay Family!The melanocortin receptor family includes MC1R, MC2R, MC3R, MC4R,...
06/10/2026

Rediscover INDIGO's Melanocortin Receptor Assay Family!
The melanocortin receptor family includes MC1R, MC2R, MC3R, MC4R, and MC5R, five GPCRs that regulate diverse physiological processes including pigmentation, steroidogenesis, energy balance, appetite, and exocrine function.

Because of their broad biology, these receptors are studied across obesity and metabolic disease, adrenal and endocrine disorders, dermatology, inflammation, and other areas of translational research.

Ready to rediscover what our MCR assays can reveal in your program? Talk to one of our scientists today! https://bit.ly/4xaENXU

Bioassays can detect the biological effects of targeted, non-targeted, and even unknown contaminants, providing a compre...
06/09/2026

Bioassays can detect the biological effects of targeted, non-targeted, and even unknown contaminants, providing a comprehensive assessment of water quality and highlighting the presence of potential risks before they become significant hazards.

Utilizing bioassays as another pillar of water quality monitoring ensures that water intended for reuse is thoroughly evaluated and safe, protecting both human health and the environment.

Learn more on our website! https://bit.ly/49OTTIL

Close the Gap Between Animal Models and Human OutcomesWe offer more than 50 alternate species receptor assays across com...
06/05/2026

Close the Gap Between Animal Models and Human Outcomes
We offer more than 50 alternate species receptor assays across commonly used laboratory species, including rat, mouse, dog, monkey, pig, and rabbit. These assays can help researchers compare receptor activity across species and improve confidence in study design and downstream interpretation.

Learn More About INDIGO’s Alternative Species Profiling Services on our Website! https://bit.ly/3RGLfG2

Rediscover INDIGO's Fibroblast Growth Factor Receptor Assay Family! The FGFR family regulate cell growth, differentiatio...
06/03/2026

Rediscover INDIGO's Fibroblast Growth Factor Receptor Assay Family!

The FGFR family regulate cell growth, differentiation, survival, and tissue repair. Because of their roles in development and disease, FGFRs are widely studied in oncology, fibrosis, skeletal disorders, metabolic disease, and regenerative medicine.

Ready to rediscover what our FGFR assays can reveal in your program? Talk to one of our scientists today! https://bit.ly/43NuGL8

Our assay uses upcyte® hepatocytes, which retain liver-specific functions such as:CYP450 enzyme activityDrug transporter...
06/02/2026

Our assay uses upcyte® hepatocytes, which retain liver-specific functions such as:

CYP450 enzyme activity
Drug transporter expression
Albumin production

Unlike immortalized cancer derived cell lines (http://e.g., HepG2), upcyte® hepatocytes are derived from healthy human liver tissue and retain more physiologically relevant functions, offering greater predictive power for assessing liver toxicity.

https://bit.ly/4dZLpQ4

If your team needs to evaluate GR-mediated repression of NF-κB signaling, INDIGO can help design a study around the ques...
05/29/2026

If your team needs to evaluate GR-mediated repression of NF-κB signaling, INDIGO can help design a study around the question that matters most.

Our scientists work with clients to develop GR/NF-κB transrepression assay strategies that align with the compound, mechanism, and stage of research. Whether the goal is early screening, compound comparison, or deeper pathway characterization, INDIGO can help define an assay approach that fits your program.

Connect with an INDIGO scientist and design your study now! https://hubs.ly/Q04hXz-p0

This recent publication titled "Assessment of chemical extracts of urban air for endocrine disruption using a serie of i...
05/28/2026

This recent publication titled "Assessment of chemical extracts of urban air for endocrine disruption using a serie of in vitro bioassays: a case study in Montreal, Canada" utilized INDIGO's AR and ERα assay kit!

"Overall, our data indicate the potential for thyroid, estrogenic, antiestrogenic and antiandrogenic disruption caused by the chemical mixtures present in the outdoor air of a major metropolis. This work provides one of the first integrated assessments of endocrine activity from atmospheric vapour phase chemical extracts, underscoring the importance of incorporating bioanalytical tools into air-quality and health-risk evaluation frameworks."

Read now by clicking on the link below 🎉

https://hubs.la/Q04hXG-l0

Address

3006 Research Drive, Suite A1
State College, PA
16801

Opening Hours

Monday 8am - 5pm
Tuesday 8am - 5pm
Wednesday 8am - 5pm
Thursday 8am - 5pm
Friday 8am - 5pm

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