Analytical Chemistry is a peer-reviewed research journal that is devoted to the dissemination of new and original knowledge in all branches of analytical chemistry. Fundamental Articles, Letters to Analytical Chemistry, and Technical Notes may address the general principles of chemical measurement science and need not directly address existing or potential analytical methodology. Manuscripts may b
e entirely theoretical with regard to analysis, or they may report experimental results that bear on theory. They may contribute to any phase of analytical measurements and concepts thereof, including but not limited to: sampling, bioanalysis, electrochemistry, mass spectrometry, microscale and nanoscale systems and structures, environmental analysis, separations, spectroscopy, chemical reactions and selectivity, instrumentation, imaging, surface analysis, and data processing. Manuscripts dealing with known analytical methods should offer a significant, original application of the method, a noteworthy improvement, or results on an important analyte. The journal also publishes Features, Perspectives, and comprehensive Reviews.