Jackson Immunoresearch

06/11/2026

Eye-specific differences in active zone addition during synaptic competition in the developing visual system. Curious to know more...click the link for the full article https://hubs.li/Q0403yx40

06/10/2026

Detection of extracellular amyloid beta aggregates by an Aducanumab-based synNotch receptor: an in vitro proof-of-concept study.

Background Synthetic Notch (synNotch) receptors are a powerful gene regulation platform that activate transcription in response to membrane-bound ligands and extracellular matrix components, with emerging applications in cancer, autoimmunity, and regenerative medicine. Whether synNotch can be adapte...

06/09/2026

SMYD3–CDCP1 Axis Drives EMT and CAF Activation in Colorectal Cancer and Is Targetable for Oxaliplatin Sensitization. Don't miss out on this interesting article

Background: Colorectal cancer (CRC) mortality is predominantly driven by liver metastasis and poor responsiveness to chemotherapy. The histone methyltransferase SMYD3 has been implicated in oncogenic transcriptional programs; however, its downstream effectors and microenvironmental roles in CRC rema...

06/09/2026

Our JIRE team members are having a great time at EACR. If you haven't already, stop by booth 16, Hall H, to learn more about our secondary antibodies and NEW reagents.

06/08/2026

Regulation of Tau Expression in Superior Cervical Ganglion (SCG) Neurons In Vivo and In Vitro.

The superior cervical ganglion (SCG) is part of the autonomic nervous system providing sympathetic innervation to the head and neck, and has been regularly used to prepare postnatal neuronal cultures for cell biological studies. We found that during development these neurons change tau expression fr...

06/08/2026

Looking forward to a week of great talks at EACR2026 in Budapest! Visit our team at booth 16, Hall H, to talk about your technical questions and pick up a T-shirt :)

06/07/2026

Ex Vivo Modulation of the BNST by Parabrachial CGRP Projections Is Decreased After a History of Stress‐Induced Anxiety. Learn more with the following article

Activity in the parabrachial calcitonin gene‐related peptide to bed nucleus of the stria terminalis (PBN[CGRP] → BNST) circuit associates with anxiety‐like behavior. To test whether previous stress‐induced anxiety is associated with neuronal ...

06/06/2026

Engineering biomimetic zonal properties in fibre-reinforced hydrogels for functional cartilage tissue engineering in vitro. Dive deeper into this topic with this fascinating article https://hubs.li/Q0403s740

06/05/2026

AIM2 drives inflammatory cell death and monkeypox pathogenesis.

Monkeypox, a zoonotic disease caused by the monkeypox virus (MPXV), has significant global public health implications. Inflammasomes serve as crucial components of the innate immune system, detecting pathogens and triggering cell death in infected cells to eliminate harmful agents. However, the prec...

06/04/2026

CryoEM and computational modeling structural insights into the pH regulator NBCn1. Follow the link to access the full article

NBCn1 plays an important role as a base loader allowing breast cancer cells to survive in an acidic environment. Here, Wang et al report its near atomic structure and transport cycle involving minimal structural changes associated with an exceptionally high turnover rate, enabling efficient cellular...