MBF Bioscience

06/12/2026

We're delighted to see this work highlighted by BioPhotonics.

HySIL and SCOPE represent exciting advances in optical design, helping deliver high-resolution 3D tissue imaging while reducing the cost and complexity traditionally associated with advanced microscopy.

We're proud to have collaborated on bringing these advances to researchers through the SLICE™ Light Sheet Microscope.

Modern biology and medicine increasingly depend on high-resolution, 3D images of intact tissues such as brains and cancer biopsies. The images allow r

06/11/2026

Great to see this work featured by Phys.org.

The article highlights the Nature Biotechnology publication from Dr. Raju Tomer and collaborators introducing HySIL and SCOPE, innovative optical technologies designed to make high-resolution 3D tissue imaging more accessible and scalable.

These advances have also been incorporated into the SLICE™ Light Sheet Microscope, helping bring powerful 3D imaging capabilities to researchers across neuroscience, developmental biology, cancer research, and pathology.

Read more: https://phys.org/news/2026-06-3d-microscope-technology-captures-high.html

A team led by Raju Tomer, professor of biological sciences at Columbia University, has created a new design for microscopes and microscope lenses that could push 3D tissue imaging beyond state-of-the-art systems while drastically cutting costs and complexity. Details of the design were published in....

06/09/2026

Exciting science news! 🎊

We're thrilled to share that Dr. Raju Tomer's laboratory at Columbia University has published major research in Nature Biotechnology—one of the world's leading journals in biotechnology and life sciences.

MBF Bioscience had the honor of supporting this work. Our SLICE light-sheet microscope—which we commercialized based on Dr. Tomer's pLSM invention—served as the platform to help validate SCOPE, a revolutionary optical technology his team developed.

The research team includes biologist collaborators from Columbia, NIH, Lehigh University, NYU Langone, and other institutions, demonstrating applications from whole-brain neuronal mapping to 3D cancer tissue imaging.

This is exactly the kind of collaboration we believe in: academic innovation creating new possibilities, with commercial partners helping make those advances accessible to researchers everywhere.

A huge congratulations to Dr. Tomer, the biologist collaborators, and all the researchers involved. We're grateful to support work that will accelerate discoveries in neuroscience, cancer research, and beyond.

Learn more: https://www.nature.com/articles/s41587-026-03172-7

Hybrid solid–liquid optics improve light-sheet imaging of intact biological samples.

06/08/2026

What a great week at the Light Sheet Fluorescence Microscopy (LSFM) Course at MDI Biological Laboratory!

Throughout the course, we showcased the SLICE Light Sheet Microscope and connected with researchers exploring a wide range of applications for light sheet imaging. The hands-on sessions and discussions created a valuable forum to exchange ideas, learn about emerging research needs, and see how light sheet microscopy continues to advance across different fields.

Thank you to the organizers, instructors, and participants for making it such a worthwhile experience. We're grateful to have been part of it and look forward to staying connected.

06/08/2026

Attending C. elegans 2026 (MAPSS + DevCell)?

Stop by our booth to see the latest in WormLab for C. elegans tracking, imaging, and behavioral analysis. Whether you're looking to improve imaging workflows or streamline behavioral studies, we'd be happy to show you what's new and discuss your research needs.

Looking forward to connecting with the C. elegans community!
https://uwmadison.eventsair.com/mapsdev26/

06/04/2026

Scientists once imagined a time when they would be able to acquire a complete subcellular-resolution 3D image of an entire mouse brain — all 600

05/20/2026

We’re having a great time at the Canadian Association for Neuroscience Meeting in Montréal!

We’re here today and tomorrow. If you’re attending, stop by our booth to see live demos of:

🔬 SLICE™ light sheet microscope for accessible, high-performance 3D imaging
🧠 FP3002 for flexible fiber photometry experiments
🧬 Software solutions for neuron tracing, stereology, brain mapping, multiphoton imaging, and more

We’d love to hear about your research and imaging workflows and connect with more of the neuroscience community!
https://can-acn.org/meeting-2026/

05/19/2026

We’re excited to share that our article, “Light-Sheet Microscope Design Puts Whole-Brain Imaging in Reach for Scientists,” is featured as the cover article in the latest issue of BioPhotonics magazine!

The article highlights how the SLICE Light Sheet Microscope system combines projected light-sheet microscopy (pLSM), advanced optics for cleared tissue, and simplified system design to make high-performance whole-brain fluorescence imaging more accessible to researchers.

From subcellular-resolution imaging to large-scale brain mapping and connectomics, this approach brings advanced 3D imaging capabilities within reach of laboratories around the world.
A huge thank you to everyone involved in the development of this technology, especially Dr. Raju Tomer and collaborators at Columbia University.

📖 Read more about how accessible light-sheet microscopy is accelerating neuroscience research and whole-brain imaging: https://www.photonics.com/Articles/Light-Sheet-Microscope-Design-Puts-Whole-Brain/p1/vo269/i1950/a72116

Scientists once imagined a time when they would be able to acquire a complete subcellular-resolution 3D image of an entire mouse brain — all 600

05/15/2026

We’re excited to be heading to Montréal for the Canadian Association for Neuroscience Meeting 2026, taking place May 18–21!

If you’re attending, stop by our booth to see live demos of:

🔬 SLICE™: our award-winning light sheet microscope built to make high-performance 3D imaging more accessible and scalable.

🧠 FP3002 Fiber Photometry System: a flexible and powerful system for recording neural activity in freely-moving animals.

We'll also be showcasing solutions for neuron tracing, stereology, brain mapping, multiphoton imaging, and more.

Can’t wait to talk science, see what everyone’s working on, and connect with the neuroscience community!
https://can-acn.org/meeting-2026/

05/06/2026

We had a great time at the AQLM course (Marine Biological Laboratory) this week showcasing the SLICE light sheet microscope and connecting with some truly passionate researchers.

A big thank you to the AQLM team for organizing such a collaborative and engaging course, and to everyone who stopped by to ask questions, share ideas, and see SLICE in action.

We’re excited to be part of a community helping make advanced imaging more accessible. 🔬