Advanced Materials Technology

Name: Advanced Materials Technology
Address: 3521 Silverside Road, Suite 1-K, Wilmington, DE, US
Telephone: +13029928060

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Advanced Materials Technology

Contact information, map and directions, contact form, opening hours, services, ratings, photos, videos and announcements from Advanced Materials Technology, Biotechnology company, 3521 Silverside Road, Suite 1-K, Wilmington, DE.

AMT developed the original HALO® Fused-Core® columns that are able to perform competitively versus sub-2 µm fully porous columns and substantially outperform 3 and 5 µm fully porous columns for high efficiency separations.

09/14/2026

Selecting the right column technology is a fundamental step in optimizing liquid chromatography methods.

Join us for an upcoming webinar hosted by CHROMacademy: "FPP vs SPP: Pros, Cons and Best Applications."

In this session, separation science experts will break down the practical differences between Fully Porous Particle (FPP) and Superficially Porous Particle (SPP) columns. The presentation will cover band broadening, backpressure management, loading capacity, and practical guidelines for determining when to utilize each stationary phase architecture for optimal chromatographic performance.

Register to attend or access the live event recording: https://bit.ly/4h0CYFW

09/07/2026

Wishing our clients, partners, and colleagues a restful and enjoyable Labor Day weekend!

Today we recognize the hard work, dedication, and ingenuity of professionals across every industry whose efforts drive progress and innovation every day.

09/04/2026

Please note that AMT will be closed on Monday, September 7th for the Labor Day holiday.

Orders received during the closure will be processed on Tuesday when our team returns.

09/02/2026

Attending ISC 2026 Prague? Join us on Tuesday, September 8, from 1 to 2 pm for a vendor lunch seminar with Dr. Stephanie Schuster.

Dr. Schuster will present "Advantages of Superficially Porous Particle Columns for HPLC and LC-MS," demonstrating how SPP technology provides high efficiency, faster analysis times, and improved column longevity compared to traditional fully porous particles.

Space is limited. Pre-register for the lunch seminar here: https://bit.ly/4cIMDzm

08/27/2026

JASIS 2026 starts next week at Makuhari Messe in Chiba, Japan!

Be sure to add booth -301 to your event itinerary. Our specialists will be available throughout the exhibition to discuss how HALO® column chemistries can enhance your laboratory productivity and method reliability.

Find full event information and pre-register here: https://bit.ly/4fHAE7a

08/25/2026

At low pH, basic compounds become positively charged which allow for unwanted interactions between the stationary phase/ silanols on the silica surface. Under high pH conditions, basic molecules become deprotonated, increasing retention (becoming less polar) and significantly improving chromatographic peak shape.

This allows for much higher sample loading capacities compared to low pH conditions as seen in the figure below. In general, you want to set the pH of your mobile phase 2 units above the analyte’s pKa value, allowing the base to become deprotonated (neutral).

08/19/2026

The AMT team will be attending ISC 2026 Prague at the Prague Congress Centre from September 6 to September 10!

ISC 2026 covers key developments across fundamental chromatographic theory, complex omics applications, and high-efficiency separations. During the symposium, our technical specialists will be available in the exhibition area to discuss customized column chemistries, bio-inert hardware options, and rapid method development strategies for challenging sample matrices.

Connect with our application specialists on the exhibition floor during the event.

Read full symposium details and register online: https://bit.ly/4qfdrwM

08/17/2026

The HALO team is heading to Japan for JASIS 2026, held September 2 to September 4 at the Makuhari Messe International Exhibition Center.

JASIS is a key global forum for showcasing cutting-edge analytical instrumentation and scientific methodologies.

Connect with our team on-site at booth 7A-301 to learn more about our latest column chemistry developments.

Learn more about the event and pre-register: https://bit.ly/4fHAE7a

08/13/2026

As oligonucleotide therapeutics become more sophisticated, complex chemical modifications present distinct analytical challenges. Next-generation siRNA therapeutics like Mivelsiran incorporate modifications such as a 2'-conjugated C16 lipid for central nervous system targeting, a 5'-E-Vinylphosphonate, and glycol nucleic acids.

Analyzing both the lipid-conjugated sense strand and the unmodified antisense strand in a single chromatographic run is notoriously difficult due to the dramatic difference in hydrophobicity between the two strands.

Our latest application note demonstrates how the HALO 1000 Å OLIGO C18 column (2.1 x 50 mm) efficiently resolves both strands of Mivelsiran in under 3 minutes, providing a robust foundation for impurity profiling and rapid pharmacokinetic screening.

Read the full application note here: https://bit.ly/4z2m0Pt

08/11/2026

Robust method development requires stationary phases that maintain stability across extreme pH ranges.

The HALO® 120 Å ELEVATE Phenyl-Hexyl column combines the pi-pi retention mechanisms of a phenyl-hexyl ligand with organo-silane surface modification. This chemistry provides exceptional alkaline tolerance, enhanced loading capacity, and superior peak shape for basic compounds at elevated pH levels.

Performance Highlights:

- Wide pH stability range (pH 2 to 12) at operating temperatures up to 60 °C.
- Improved peak symmetry for basic analytes.
- Scalable across UHPLC and HPLC systems with 2, 2.7, and 5 µm particle options.
- Fully endcapped L11 phase with a 5.1% carbon load.

Explore technical data and column dimensions: https://bit.ly/4wSCfwU

Address

3521 Silverside Road, Suite 1-K
Wilmington, DE

Telephone

+13029928060

Website

http://www.halocolumns.com/

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