Advanced Materials Technology

Name: Advanced Materials Technology
Address: 3521 Silverside Road, Suite 1-K, Wilmington, DE, US
Telephone: +13029928060

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Advanced Materials Technology

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AMT developed the original HALO® Fused-Core® columns that are able to perform competitively versus sub-2 µm fully porous columns and substantially outperform 3 and 5 µm fully porous columns for high efficiency separations.

06/19/2026

Today, we honor the historical significance of June 19th, and recognize the enduring journey toward freedom, equality, and opportunity for all.

We wish everyone a meaningful and safe holiday!

06/16/2026

Did you know June 16th is National Fresh Veggies Day? This application note highlights the analysis of spinach which is one of the most nutrient-dense leafy greens available globally.

Characterizing fat-soluble vitamins in complex botanical matrices requires high-resolution stationary phases. In this application, a spinach sample was extracted in hexane and analyzed using a HALO® C30 column. To demonstrate baseline resolution under efficient isocratic HPLC conditions, the matrix was evaluated alongside a standard spike of Vitamins A, D2, and K1.

The shape-selectivity of the HALO® C30 phase provides the critical resolution needed for complex hydrophobic compounds, making it an excellent choice for food quality and nutritional analysis.

Read the full application note to view the chromatogram and method parameters: https://bit.ly/3TIUpjB

06/10/2026

We're excited to introduce the HALO® ELEVATE product extension!

HALO® ELEVATE represents the innovation in superficially porous particle technology, designed to extend the performance of UHPLC separations while maintaining the efficiency advantages associated with HALO® design.

Built on our new high pH stable particle technology, the ELEVATE extension is developed to provide flexibility in the lab. With three phases and three particle sizes to choose from – the user can confidently utilize this product across the pH range, achieve the retention and peak shapes they need all while operating at either low or high pH conditions.

As chromatographic demands continue to increase in complexity, HALO® ELEVATE provides a scalable option for scientists seeking greater analytical confidence without compromising throughput.

Learn more at https://bit.ly/4bYJgl1

06/08/2026

We're at HPLC 2026!

Our technical team will be presenting several key sessions today including:

• Conner McHale (Poster): Improved HPLC Method Development using Wide pH Range | 10:00–11:00 AM
• Peter Pellegrinelli: Advancing Positively Charged Surface Stationary Phase Technology with 2 µm Particles | 11:30–11:50 AM
• Will Miles: Assessment of Stationary Phase Ligands on Positively Charged Particles | 2:40–3:00 PM
• Dr. Barry Boyes: Pore Size Effects of Hybrid Superficially Porous Particles on Nucleic Acids Separations | 5:40–6:00 PM

We look forward to a week of collaboration and scientific innovation.

Full schedule and presentation details: https://bit.ly/49xV2nA

06/04/2026

In recognition of National Candy Month, our latest application note focuses on sugar profile analysis in complex food matrices. Quantifying sucrose and lactose across different chocolate formulations requires a highly selective stationary phase capable of handling complex fat and protein matrices.

We demonstrate the separation of these key carbohydrates in milk, white, and dark chocolate using HILIC mode coupled with an evaporative light scattering detector (ELSD). The workflow utilizes the HALO® Penta-HILIC column, which features a polar ligand with five hydroxyl groups tethered to Fused-Core® silica particles for enhanced selectivity of hydrophilic compounds.

Read the full application note to view the method parameters and chromatograms: https://bit.ly/4rI4Sdt

06/02/2026

While most LCMS methods are performed in positive polarity, some such as oligonucleotide analysis are typically run at high pH in negative mode. This can invite the formation of metal adduction from the presence of Na+, K+, and others which can complicate the interpretation of MS data.

There are a number of steps you can take to minimize the presence of these cations such as the use of Type-1, 18 MOhm water, minimizing the use of borosilicate glass for storage of buffers, using polycarbonate instead, and using LCMS grade reagents that are certified free of alkali metals.

For example, hexafluoroisopropanol, which is commonly used in oligonucleotide LCMS buffers can frequently contain considerable amounts of alkali. Using LCMS grade such as the Supelco Lichropur HFIP, will make your results much easier to interpret and reliable.

05/30/2026

Advanced Materials Technology invites you to connect with our scientific specialists starting this weekend at ASMS 2026! Visit us at Booth #309 to discuss your lab's complex separation challenges and discover the latest advancements in Fused-Core® technology.

Our featured Wednesday line-up includes:
• Corporate Breakfast Seminar: Join Dr. Josh McBee for an in-depth session on mastering oligonucleotide analysis via LCMS using the HALO® 1000 Å OLIGO C18 column. Registration required: https://bit.ly/4uC0cHM
• Poster Presentations: Meet Peter Pellegrinelli and Dr. Barry Boyes during the afternoon session to review new data on advanced stationary phases and synthetic oligonucleotide separations.

View our complete presentation schedule, poster numbers, and learn more at: https://halocolumns.com/halo-at-asms-2026/

05/28/2026

Join HALO® at The American Society for Mass Spectrometry (ASMS) 2026 Breakfast Seminar on Oligonucleotide Analysis!

Oligonucleotide-based therapeutics present unique analytical challenges. While LC/MS is vital for critical quality attribute (CQA) testing, their large size, hydrophilic nature, and separation complexities require specialized chromatographic approaches.

Join Dr. Josh McBee and the Advanced Materials Technology team to explore a robust framework for proper method development using the HALO 1000 Å OLIGO C18 HPLC column.

Seminar Details:
• Topic: Mastering The Art of Oligonucleotide Analysis via LCMS Using The HALO 1000 Å OLIGO C18 HPLC Column
•Date/Time: Wednesday, June 3, 2026 | 7:00 AM – 8:00 AM (Light breakfast provided)
• Location: Room 1A

Space is limited. Register at: https://bit.ly/4uC0cHM

05/25/2026

This Memorial Day, we remember and honor the men and women who gave their lives in service to the country.

Wishing everyone a safe and meaningful holiday as we take time to reflect and recognize their sacrifice.

05/22/2026

We’ll be attending HPLC 2026 in Indianapolis, IN from June 6–11. Stop by Booth #311 to connect with the team and learn more about the latest developments in chromatography and separation science.

AMT will also be presenting several talks throughout the conference:

Peter Pellegrinelli: Sharper Peaks and Higher Sensitivity: Advancing Positively Charged Surface Stationary Phase Technology with 2 µm Particles
June 8, 2026 | 11:30–11:50 AM

Barry Boyes, PhD: Selectivity and Efficiency Effects of Pore Size of Hybrid Superficially Porous Particles on Nucleic Acids Separations
June 8, 2026 | 5:40–6:00 PM

Will Miles: Assessment of Stationary Phase Ligands on Positively Charged Particles by
an Anionic Exchange Parameter
June 8, 2026 | 2:40PM – 3:00PM

Conner McHale: Poster: Improved HPLC Method Development using Wide pH Range
June 8, 2026 | 10:00–11:00 AM

Looking forward to another great week of science, collaboration, and innovation at HPLC 2026!

For more information visit: https://bit.ly/49xV2nA

Address

3521 Silverside Road, Suite 1-K
Wilmington, DE

Telephone

+13029928060

Website

http://www.halocolumns.com/

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