Lipotype

Name: Lipotype
Address: Blasewitzer Str. 58, Dresden, 01307, DE
Telephone: +493512598950

Researchers of , the leading lipidomics service provider, explain and what happens

03/09/2026

New publication: Targeting nucleolin makes glioblastoma cells fragile
---

Glioblastoma is among the most treatment-resistant brain cancers. In part because it can survive treatments like chemotherapy and radiation by rewiring its cells' metabolism. A new study targeted nucleolin, a protein overexpressed on glioblastoma cell surfaces, using AS1411. AS1411 is a short DNA aptamer, a folded strand of DNA engineered to bind a target with antibody-like precision.

This treatment shifted tumor cell membranes toward a more rigid, saturated lipid composition, while also enriching lipids that fuel ferroptosis, a form of cell death driven by lipid oxidation. Together, these changes create a potential opening: cells under this stress may become more susceptible to therapies that push them toward ferroptotic death.

Lipotype's quantitative, species-level lipidomics analysis can be used to profile such lipid shifts across conditions.

Read the full article here: https://www.lipotype.com/lipidomics-resource-center/?q=AS1411-Induced+Lipidomic+Alterations+and+Therapeutic+Insights+in+U-87+Glioblastoma+Cells

02/09/2026

Dresden is full of flavor(s) — and so is Lipotype
---

On August 31, Lipotype joined the banquet "Dresden is(s)t bunt," a celebration of diversity, openness, and respectful coexistence in Dresden, Germany. For its 10th edition in 2026, the event transformed Neumarkt around the Frauenkirche into one long communal table, bringing people together through conversation, culture, and shared experiences.

With 107 cultural partners and 98 sponsors participating, the banquet sent a strong message in support of an inclusive and welcoming Dresden.

This spirit of coming together reflects many of Lipotype's core values. As an international team, we believe that creativity, collaboration, and growth flourish in an open and welcoming community with diverse perspectives and meaningful connections. We were grateful to be part of a celebration that brought together so many people and organizations in support of a vibrant, inclusive, and forward-looking Dresden.

31/08/2026

“It Came at Exactly The Right Time”
An Interview with the 2019 LEA Winner, Prof. Dr. Oliver Schmidt
---

In 2019, the Lipotype Excellence Award (LEA) was awarded to Prof. Dr. Oliver Schmidt from the Medical University of Innsbruck, Austria, to support research on the EGAD protein degradation pathway.
The research revealed that when certain membrane proteins accumulate, cells respond by altering their membrane lipid composition, enabling them to accommodate proteins that cannot be properly degraded. This data contributed to a Nature Communications paper published in 2024.

We spoke with Prof. Dr. Oliver Schmidt about his research and the role LEA played in helping him advance his work at a crucial moment in his career. Read the full interview here: https://www.lipotype.com/corporate-news/it-came-at-exactly-the-right-time/

# Sphingolipids

28/08/2026

Lipotype Open Day & Networking Event 🙌
---

Last Tuesday, on August 25th, Lipotype had the pleasure of welcoming both familiar faces and new connections from MPI-CBG - Max Planck Institute of Molecular Cell Biology and Genetics alums to our new office for the Lipotype Open Day & Networking Event.

During the networking session at MPI-CBG's 25th anniversary celebrations, visitors attended guided tours at Lipotype, seeing our new laboratory and office space at ADDRESS HERE. Melanie Weber, Kai Schuhmann and Jaekyung Pyo hosted the tours, followed by a Q&A session with team members from across the company.

We were happy to meet the crowd and share our favorite things about Lipotype. As a spin-off company founded from the laboratories of Kai Simons and Andrej Shevchenko at the MPI-CBG, hosting this event was particularly heartwarming for Lipotype members. We are grateful to everyone who attended and helped make the event such a success.

Special thanks to Jaekyung Pyo for leading the event organization, Olya Vvedenskaya, MD, PhD for promoting the event, Jeongeun Chae, EunGyeom Kim, and Sehui Myung for organizing the event and encouraging participation. Of course, we also would like to thank the whole Lipotype team for their participation, enthusiasm, and support in making the event successful!

14/08/2026

New publication: Mitochondrial stress pushes brain immune cells toward senescence
---

Microglia, the brain's resident immune cells, support neuron health, yet how mitochondrial stress shapes them in the human brain has remained unclear. A new study finds that mitochondrial stress pushes human microglia into a senescent, dysfunctional state. It does so by depleting a key metabolic molecule, S-adenosylmethionine, and remodeling their lipids. This disrupts the signals microglia send to neighboring neurons and glia. Researchers modeled this shift directly in human brain organoids, where it triggered inflammatory signaling linked to neurodegenerative disease. The findings point to microglial aging as a specific contributor to neurodegenerative disease.

Lipotype lipidomics enables detailed profiling of the lipid changes that accompany cellular aging processes.

Read the full article here: https://www.lipotype.com/lipidomics-resource-center/?q=The+mitochondrial+unfolded+protein+response+in+human+microglia+disrupts+neuronal+glial+communication+and+promotes+senescence

13/08/2026

Welcome Sehui!
---

We are excited to announce that Sehui Myung has joined Lipotype as our new Marketing Intern!

Sehui is completing a Bachelor's degree in English Literature with a double major in Lifelong Education at Soongsil University in South Korea. She previously interned in marketing, where she managed Naver Blog content and helped grow brand awareness through content marketing.

With her experience in digital marketing and content management, Sehui brings valuable skills to the team. At Lipotype, she will support various marketing activities including content marketing and event management.

Please join us in giving a warm welcome to Sehui!

11/08/2026

What’s New in Skin Barrier Evaluation?
---

Lipotype is co-hosting a webinar " Skin Barrier Evaluation: What's New?" with Skinobs presented by Anne Charpentier and Dr. Olya Vvedenskaya, on August 27th, 2026, at 4:00 PM CEST.

Join us to explore how skin barrier function is actually measured nowadays and the latest approaches to skin barrier assessment. Lipotype will present lipidomics analysis that is used in formulators development and claim support in dermatology.

Secure your spot now! 👉 https://www.lipotype.com/lipidomics-webinars/skinobs/

10/08/2026

Meet us at Kern Lipid Conference in Breckenridge, USA!
---

Join Lipotype at the Kern Lipid Conference 2026 in Breckenridge, Colorado, from August 10 to 12. The event brings together lipid researchers to exchange the latest developments in lipid biology, analytics, and methodology. This year's sessions span lipid and lipoprotein biology across neurodegenerative, cardiometabolic, and immune disease, from signaling pathways and apolipoprotein biology to lipid droplet dynamics and emerging lipid analysis technologies.

Come find Dr. Alessia Trimigno, Scientific Account Manager, and Dr. Christian Klose, CTO of Lipotype, at our exhibit table in the 3rd Floor Foyer throughout the conference. They're happy to discuss lipidomics workflows and how quantitative lipid analysis could support your research.

We look forward to meeting you there!

Read the details here: https://kernconference.org/index.html

06/08/2026

New case study: Advancing clinical lipidomics through quantification
---

Lipidomics is a great addition to precision medicine, but there's an issue we as a community need to keep addressing: measurements of the same lipids often differ from lab to lab, making results hard to compare or validate.

In 2017, lipidomics labs from all over the world put this to the test. Lipotype and 30 other laboratories each analyzed the same human plasma reference sample. The results pointed to one main culprit: the internal standards each lab used were different. Internal standards are the reference molecules of known concentration, added to calibrate lipid measurements. The use of different internal standards could explain most of the variation between labs.

The study turned this into a solution: consensus values, agreed reference concentrations for 339 lipids that any lab can now use to check and validate its own measurements. Lipotype lipidomics delivers absolute, reproducible lipid quantification for translational and clinical research.

Read the full case study here: https://www.lipotype.com/lipidomics-applications/advancing-clinical-lipidomics-through-quantification/

03/08/2026

August is Immunization Awareness Month
---

Immunization Awareness Month reminds us that vaccination remains one of the most effective tools for protecting people of all ages from serious disease. The need for that protection does not end in childhood. It continues throughout life, and specific recommendations change with age.

That protection depends on more than the antigen, the substance in a vaccine that trains the immune system to recognize a specific pathogen. Vaccine adjuvants, like the lipid-based AS03, boost the immune response so smaller antigen doses still trigger lasting immunity. Lipidomics research has shown this works by reshaping cholesterol and phospholipid metabolism in immune cells.

Lipotype lipidomics analyses help researchers investigate these mechanisms, supporting the development of more effective vaccines.

Read the details here: https://www.lipotype.com/lipidomics-applications/lipidomics-in-vaccine-research/

Adresse

Blasewitzer Str. 58
Dresden
01307

Telefon

+493512598950

Webseite

http://www.lipotype.com/

Benachrichtigungen

Lassen Sie sich von uns eine E-Mail senden und seien Sie der erste der Neuigkeiten und Aktionen von Lipotype erfährt. Ihre E-Mail-Adresse wird nicht für andere Zwecke verwendet und Sie können sich jederzeit abmelden.