16/10/2026
October is , a time to highlight advances in research that improve our understanding of breast cancer progression.
The bone marrow is a frequent site of breast cancer metastasis and contributes substantially to patient morbidity and mortality worldwide. New research highlights the OPG/RANKL axis as an important immune-related pathway in breast cancer bone metastasis, based on data from a preclinical model.
Key insights:
▪️ OPG-producing B cells were associated with reduced bone metastatic burden
▪️ RANKL-expressing T cells were linked to increased metastatic risk
👉 The findings reinforce the relevance of OPG and RANKL as biomarkers in bone biology, osteoimmunology, and translational cancer research
At Biomedica, our human OPG and RANKL ELISA assay kits support researchers studying these pathways in human samples.
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