Cell Signaling Technology, Inc.

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Cell Signaling Technology, Inc. Cell Signaling Technology develops and produces antibodies, kits, and reagents used to study the cell signaling pathways that impact human health.

For Research Use Only. Not for Use in Diagnostic Procedures. Active in the field of applied systems biology research, particularly as it relates to cancer, CST understands the importance of using antibodies with high levels of specificity and lot-to-lot consistency. It’s why we produce all of our antibodies in house, and perform painstaking validations for multiple applications. And the same CST scientists who produce our antibodies also provide technical support for customers, helping them design experiments, troubleshoot, and achieve reliable results. We do this because that’s what we’d want if we were in the lab. Because, actually, we are.

🍂🧬Are senescent cells in your model protecting against cancer—or quietly helping it adapt and resist therapy?👉Learn more...
10/23/2026

🍂🧬Are senescent cells in your model protecting against cancer—or quietly helping it adapt and resist therapy?

👉Learn more about the dual role of SASP on tumor suppression and progression—including how it drives inflammation, ECM remodeling, and stromal reprogramming. Discover emerging senescence-targeted strategies, such as senolytics and senomorphics, on the .

Explore how senescent cells and SASP shape the tumor microenvironment, influence cancer hallmarks, and inform emerging senolytic and senomorphic therapies.

🔀 A *twist* of fate in tumor evolution? When EMT drivers like TWIST, ZEB1, and Snail rewire cellular identity, cancer ce...
10/22/2026

🔀 A *twist* of fate in tumor evolution? When EMT drivers like TWIST, ZEB1, and Snail rewire cellular identity, cancer cells can gain phenotypic plasticity—and potentially develop therapy resistance.

👉 Explore key EMT signatures, pluripotency markers, and “stemness” targets on the .

Learn how mechanisms like dedifferentiation and transdifferentiation contribute to phenotypic plasticity to drive cancer progression and therapy resistance

Inflammasome Therapeutics: How the Inflammasome Pathway is Being Targeted to Treat Chronic Diseases - Explore how target...
10/21/2026

Inflammasome Therapeutics: How the Inflammasome Pathway is Being Targeted to Treat Chronic Diseases - Explore how targeting inflammasome pathways leads to novel therapeutics for chronic diseases on the CST Blog.

Explore how targeting inflammasome pathways leads to novel therapeutics for chronic diseases on the CST Blog.

WEBINAR: Do you want publication-ready IHC/IF images, every time? 🔬Join us for our live Applications 101 webinar, See th...
10/21/2026

WEBINAR: Do you want publication-ready IHC/IF images, every time? 🔬

Join us for our live Applications 101 webinar, See the Signal: Master IHC & IF Staining. Get practical tips and tricks for successful imaging results. Bonus: learn how to move to multiplexing.

📅 Date: October 29 | 8:00 AM & 4:00 PM CET
👉 Save your spot: https://hubs.ly/Q04z8p1q0

🧬🫸 Where will next-generation inhibitors, targeted protein degradation (TPD), and combo therapies take the study of cell...
10/19/2026

🧬🫸 Where will next-generation inhibitors, targeted protein degradation (TPD), and combo therapies take the study of cell proliferation? Completely halting proliferative signaling is challenging due to pathway redundancy, resistance, and rewiring. Discover how recent advances in drug design are overcoming this challenge to create more effective, targeted cancer treatments. Learn more about the Cancer Hallmark: Sustaining Proliferative Signaling on the .

A Hallmark of Cancer, sustaining proliferative signaling is used by cancer cells to stimulate growth and relies on Akt, MAPK/Erk, and MTOR pathways.

The genetic cause of Huntington’s disease is known—but its downstream biology remains complex. Explore key HD biomarkers...
10/16/2026

The genetic cause of Huntington’s disease is known—but its downstream biology remains complex. Explore key HD biomarkers, from mHTT and NfL to DARPP-32 and YKL-40, along with validated CST antibody tools for studying them.

Explore key Huntington's disease biomarkers and validated CST antibodies for studying mHTT, neuronal loss, striatal dysfunction, and neuroinflammation.

💀 Resisting cell death is a textbook hallmark of cancer—but do you know how your model is really doing it?👉 From caspase...
10/16/2026

💀 Resisting cell death is a textbook hallmark of cancer—but do you know how your model is really doing it?

👉 From caspases and Bcl‑2 family members to IAPs and BH3‑only “gatekeepers,” see which signaling nodes tumors hijack to resist apoptosis and survive cellular stress and damage on the .

Discover how cancer cells evade apoptosis and other death pathways and explore key targets, markers and tools to study the Hallmark of Resisting Cell Death

Discover how CST chimeric monoclonal antibodies enable low-plex, multi-species imaging of key brain cell markers with gr...
10/14/2026

Discover how CST chimeric monoclonal antibodies enable low-plex, multi-species imaging of key brain cell markers with greater panel flexibility.

Poster Presentation Details:
📆 Day: 14-15 October
⏰ Time: 13:30 - 14:00
🖼️ Poster #: 238

Stop by our poster at ELRIG Drug Discovery 2026 to chat with our team, or visit our booth to learn more!

🧬🔬Trying to identify the epigenetic reprogramming mechanism responsible for the change in gene expression? Analyze epige...
10/12/2026

🧬🔬Trying to identify the epigenetic reprogramming mechanism responsible for the change in gene expression? Analyze epigenetic regulator proteins via chromatin profiling to identify changes in epigenetic signatures across the genome.

👉 Explore key DNA methylation and histone modification targets plus CST antibodies and chromatin profiling kits on the .

Learn how cancer epigenetics uses DNA methylation and histone modification to fuel nonmutational epigenetic reprogramming, a hallmark in tumor biology.

🔥🧰 Need to interrogate a complex inflammatory microenvironment? Enhance your IHC, IF, Flow, or WB experiments by combini...
10/08/2026

🔥🧰 Need to interrogate a complex inflammatory microenvironment? Enhance your IHC, IF, Flow, or WB experiments by combining markers for neutrophils and monocytes, M1/M2‑like macrophages, MDSCs, checkpoint ligands, and inflammasome components to build a clearer picture of the TME.

👉 Tap an expert‑curated shortlist of inflammatory pathways and cell markers to build your Tumor‑Promoting Inflammation research toolbox using the Hallmarks of Cancer .

Cancer cells hijack inflammatory mechanisms to promote their own growth and survival.

Address

3 Trask Lane
Danvers, MA
01923

Opening Hours

Monday 8:30am - 8pm
Tuesday 8:30am - 8pm
Wednesday 8:30am - 8pm
Thursday 8:30am - 8pm
Friday 8:30am - 8pm

Telephone

+19788672300

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